| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
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0.070 | GeneticVariation | BEFREE | One of the lead single nucleotide polymorphisms, rs10757278, was mostly investigated in association with coronary artery disease but rarely with carotid atherosclerosis. | 26941057 | 2016 |
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0.070 | GeneticVariation | BEFREE | Recently independent studies reported an association between coronary heart disease and single-nucleotide polymorphisms (SNPs) located at chromosome 9p21 (rs10757278 and proxy SNPs). | 24625579 | 2014 |
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0.070 | GeneticVariation | BEFREE | Common variants in the 9p21.3 locus have been reported to be associated with multiple cardiovascular phenotypes, including coronary artery disease and intracranial aneurysms (rs10757278 and rs1333040). | 24777168 | 2014 |
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0.070 | GeneticVariation | BEFREE | A case-control study to investigate the association of the 9p21 single nucleotide polymorphisms (SNPs) rs10757274 and rs10757278 (known to be associated with coronary artery disease [CAD] risk) with peripheral arterial disease (PAD), in a Han Chinese population. | 23569135 | 2013 |
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0.070 | GeneticVariation | BEFREE | The risk variant on chromosome 9, tagged by rs10757278, is associated with coronary heart disease in the Belgian population, but not with isolated CVD. | 19319159 | 2009 |
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0.070 | GeneticVariation | BEFREE | Significantly reduced expression of all INK4/ARF transcripts (p15(INK4b), p16(INK4a), ARF and ANRIL) was found in PBTL of individuals harboring a common SNP (rs10757278) associated with increased risk of coronary artery disease, stroke and aortic aneurysm. | 19343170 | 2009 |
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0.070 | GeneticVariation | BEFREE | Conclusions The rs10757278 and rs2383207 variants are determinants for early-onset coronary artery disease. | 18459066 | 2009 |