Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs397507444
rs397507444
0.090 GeneticVariation BEFREE The association of the A1298C polymorphism with three diseases (coronary heart disease, breast cancer and neural tube defects fathers) was statistically significant (p < 0.05). 27888505

2017

dbSNP: rs397507444
rs397507444
0.090 GeneticVariation BEFREE Homocysteine and methylenetetrahydrofolate reductase C677T and A1298C polymorphisms in Tunisian patients with severe coronary artery disease. 18204887

2009

dbSNP: rs397507444
rs397507444
0.090 GeneticVariation BEFREE Methylenetetrahydrofolate reductase gene, homocysteine and coronary artery disease: the A1298C polymorphism does matter. Inferences from a case study (Madeira, Portugal). 18384842

2008

dbSNP: rs397507444
rs397507444
0.090 GeneticVariation BEFREE We studied several single nucleotide polymorphisms (SNP) in Hcy-regulating genes [methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C; methionine synthase (MS) A2756G; methionine synthase reductase (MTRR) A66G] in relation to total plasma Hcy levels, transplant coronary artery disease and thromboembolic episodes in 84 heart transplant patients, and we compared the incidence of these polymorphisms with those in a healthy adult controls. 15612980

2005

dbSNP: rs397507444
rs397507444
0.090 GeneticVariation BEFREE Association of MTRRA66G polymorphism (but not of MTHFR C677T and A1298C, MTRA2756G, TCN C776G) with homocysteine and coronary artery disease in the French population. 16268464

2005

dbSNP: rs397507444
rs397507444
0.090 GeneticVariation BEFREE Methylenetetrahydrofolate reductase gene C677T and A1298C polymorphisms, plasma homocysteine, folate, and vitamin B12 levels and the extent of coronary artery disease. 15135689

2004

dbSNP: rs397507444
rs397507444
0.090 GeneticVariation BEFREE We investigated the influence of elevated homocysteine plasma levels and 2 polymorphisms, 677C/T and 1298A/C, of the methylenetetrahydrofolate reductase (MTHFR) gene on the risk of restenosis after stenting in patients with symptomatic coronary artery disease. 14604831

2003

dbSNP: rs397507444
rs397507444
0.090 GeneticVariation BEFREE Prevalence and role of methylenetetrahydrofolate reductase 677 C-->T and 1298 A-->C polymorphisms in coronary artery disease in Arabs. 14521457

2003

dbSNP: rs397507444
rs397507444
0.090 GeneticVariation BEFREE These findings do not support a major role for the A1298C mutation in homocysteine metabolism and emphasize the hypothesis that MTHFR genotypes may interfere with coronary artery disease risk only when an unbalanced nutritional status leads to raised total plasma homocysteine levels. 12049191

2002