Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4986790
rs4986790
0.060 GeneticVariation BEFREE Association between Toll-like receptor 4 Asp299Gly polymorphism and coronary heart disease susceptibility. 28793055

2017

dbSNP: rs4986790
rs4986790
0.060 GeneticVariation BEFREE TLR4 gene polymorphism (Asp299Gly) attenuates innate immune responsiveness, reduces the risk for coronary artery disease, and increases a chance of longevity. 19273219

2009

dbSNP: rs4986790
rs4986790
0.060 GeneticVariation BEFREE We studied the TLR4 gene Asp299Gly polymorphism in relation to susceptibility to myocardial infarction in a cohort of patients with angiographically documented coronary artery disease, and performed a meta-analysis using data sets from three independent studies. 15864121

2005

dbSNP: rs4986790
rs4986790
0.060 GeneticVariation BEFREE Toll-like receptor 4 gene Asp299Gly polymorphism is associated with reductions in vascular inflammation, angiographic coronary artery disease, and clinical diabetes. 15632890

2004

dbSNP: rs4986790
rs4986790
0.060 GeneticVariation BEFREE Among symptomatic men with documented coronary artery disease, the TLR4 Asp299Gly polymorphism was associated with the risk of cardiovascular events. 12742999

2003

dbSNP: rs4986790
rs4986790
0.060 GeneticVariation BEFREE The findings of this study do not support the hypothesis that the TLR4 Asp299Gly polymorphism influences predisposition to and progression of coronary artery disease. 12957699

2003