Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs662
rs662
0.100 GeneticVariation BEFREE Association between the PON1 Q192R polymorphism and coronary heart disease in Chinese: A meta-analysis. 29952962

2018

dbSNP: rs662
rs662
0.100 GeneticVariation BEFREE The activity of PON1 is decreased in patients with coronary artery disease, myocardial infarction or chronic kidney disease. rs662 and rs854560 are single nucleotide polymorphisms (SNPs) associated with PON1 activity and 10-year cardiovascular mortality of patients with stable coronary artery disease. 25155309

2016

dbSNP: rs662
rs662
0.100 GeneticVariation BEFREE Association between PON1 rs662 polymorphism and coronary artery disease. 24918121

2014

dbSNP: rs662
rs662
0.100 GeneticVariation BEFREE Association of paraoxonase1 gene Q192R polymorphism and apolipoprotein B in Asian Indian women with coronary artery disease risk. 23171143

2013

dbSNP: rs662
rs662
0.100 GeneticVariation BEFREE The Q192R polymorphism of the paraoxonase 1 gene is a risk factor for coronary artery disease in Saudi subjects. 23625196

2013

dbSNP: rs662
rs662
0.100 GeneticVariation BEFREE We tested the clinical relevance of the PON1 Q192R genotype in a population of individuals with coronary artery disease who underwent stent implantation and received clopidogrel therapy. 21170047

2011

dbSNP: rs662
rs662
0.100 GeneticVariation BEFREE Interaction of folate intake and the paraoxonase Q192R polymorphism with risk of incident coronary heart disease and ischemic stroke: the atherosclerosis risk in communities study. 21982484

2011

dbSNP: rs662
rs662
0.100 GeneticVariation BEFREE A preliminary study of human paraoxonase and PON 1 L/M55-PON 1 Q/R 192 polymorphisms in Turkish patients with coronary artery disease. 19226538

2009

dbSNP: rs662
rs662
0.100 GeneticVariation BEFREE Paraoxonase-1 (PON1) activity, but not PON1(Q192R) phenotype, is a predictor of coronary artery disease in a middle-aged Serbian population. 17032132

2006

dbSNP: rs662
rs662
0.100 GeneticVariation BEFREE The association of the PON1 Q192R polymorphism with coronary heart disease: findings from the British Women's Heart and Health cohort study and a meta-analysis. 15214960

2004

dbSNP: rs662
rs662
0.100 GeneticVariation BEFREE Different pattern of association of paraoxonase Gln192-->Arg polymorphism with sporadic late-onset Alzheimer's disease and coronary artery disease. 12618290

2003

dbSNP: rs662
rs662
0.100 GeneticVariation BEFREE PON1 L55M polymorphism is not a predictor of coronary atherosclerosis either alone or in combination with Q192R polymorphism in an Italian population. 11851721

2002

dbSNP: rs662
rs662
0.100 GeneticVariation BEFREE The Q/R192 variants of PON1 are not associated with severity, progression or regression of coronary atherosclerosis, plasma lipid levels, clinical events, or response to treatment with fluvastatin. 11257264

2001

dbSNP: rs662
rs662
0.100 GeneticVariation BEFREE Coronary artery disease risk in Chinese type 2 diabetics: is there a role for paraxonase 1 gene (Q192R) polymorphism? 11375798

2001

dbSNP: rs662
rs662
0.100 GeneticVariation BEFREE Its enzymatic serum activity varies 10-40-fold between individuals, and its biallelic gene polymorphism at codon 192 (glutamine-->arginine, Gln/Arg) has been associated with coronary artery disease in diabetic patients. 11409295

2001

dbSNP: rs662
rs662
0.100 GeneticVariation BEFREE Studies have been conducted to evaluate the possible "protective" role of PON, and especially the influence of the Arg-->Gln 192 polymorphism, in coronary artery disease. 9746266

1998