| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
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0.100 | GeneticVariation | BEFREE | Relationship of the rs1799752 polymorphism of the angiotensin-converting enzyme gene and the rs699 polymorphism of the angiotensinogen gene to the process of in-stent restenosis in a population of Polish patients with stable coronary artery disease. | 27162064 | 2016 |
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0.100 | GeneticVariation | BEFREE | The M235T single nucleotide polymorphism in the angiotensinogen gene is associated with coronary artery calcium in patients with a family history of coronary artery disease. | 23137822 | 2013 |
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0.100 | GeneticVariation | BEFREE | AGT gene polymorphisms (M235T, T174M) are associated with coronary heart disease in a Chinese population. | 22791700 | 2013 |
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|
0.100 | GeneticVariation | BEFREE | Angiotensinogen gene M235T polymorphism and risk of coronary artery disease: a meta-analysis. | 22842872 | 2012 |
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0.100 | GeneticVariation | BEFREE | The M235T polymorphism of the AGT gene modifies the risk of coronary artery disease associated with the presence of hypercholesterolemia. | 18409009 | 2008 |
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|
0.100 | GeneticVariation | BEFREE | The angiotensinogen M235T variant was analyzed in 871 consecutive patients with clinically suspected coronary artery disease submitted to coronary angiography study. | 16045904 | 2005 |
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0.100 | GeneticVariation | BEFREE | The angiotensinogen M235T polymorphism is positively associated with plasma angiotensinogen, hypertension, and coronary heart disease. | 12040348 | 2002 |
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0.100 | GeneticVariation | BEFREE | Association of angiotensinogen M235T and A(-6)G gene polymorphisms with coronary heart disease with independence of essential hypertension: the PROCAGENE study. Prospective Cardiac Gene. | 11345362 | 2001 |
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|
0.100 | GeneticVariation | BEFREE | In 257 Dutch IDDM patients (188 with urinary albumin excretion (UAE) <30 mg/24 h), logistic regression analysis was used to study the relationships among, on the one hand, the insertion/deletion gene polymorphism of the angiotensin-converting enzyme gene (ACE-ID), the M235T gene polymorphism of the angiotensinogen gene (AGT-M235T), and the A1166C gene polymorphism of the angiotensin type 1 receptor gene (AT1-A1166C), and, on the other hand, UAE, retinopathy, hypertension, and coronary heart disease. | 10862638 | 2000 |
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0.100 | GeneticVariation | BEFREE | The significant relations observed between the AGT M235T variant, its protein product, and the cardiovascular disease phenotypes provide evidence for a possible role of elevated circulating AGT in the pathogenesis of coronary artery disease. | 10097233 | 1999 |
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|
0.100 | GeneticVariation | BEFREE | Angiotensinogen T174M and M235T gene polymorphisms are associated with the extent of coronary atherosclerosis. | 10488958 | 1999 |