|
rs1004467
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.
|
21347282 |
2011 |
|
rs10069690
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genetic model analysis revealed that rs10069690 was associated with an increased risk of CHD under co-dominant, dominant, over-dominant and log-additive models.
|
28978050 |
2017 |
|
rs1008438
|
|
|
0.010 |
GeneticVariation |
BEFREE |
By resequencing and genotyping, the associations of 2 single nucleotide polymorphisms (SNPs) +190G/C (rs1043618) and -110A/C (rs1008438) in the HSPA1A gene with risk of CHD were determined in a 1,003 pairs case-control study.
|
19333379 |
2009 |
|
rs1010
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Single nucleotide polymorphisms (SNPs) at the KIF6 (kinesin like protein 6, rs20455 or 719Arg), LPA (lipoprotein(a), rs3798220), TAS2R50 (taste receptor type 2, member 50, rs1376251) and VAMP8 (vesicle-associated membrane protein 8, rs1010) have previously been associated with low density lipoprotein cholesterol (LDL-C) lowering response to statins, coronary heart disease (CHD) at baseline, or CHD events on trial.
|
22192511 |
2012 |
|
rs1010
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We considered five variants that were associated with coronary heart disease in two studies and confirmed in the Atherosclerosis Risk in Communities study: rs20455 (KIF6), rs3900940 (MYH15), rs7439293 (PALLD), rs2298566 (SNX19), and rs1010 (VAMP8).
|
18073581 |
2007 |
|
rs10116277
|
|
|
0.010 |
GeneticVariation |
BEFREE |
With the exception of rs1333040, whites with at least one copy of the 9p21 SNP risk alleles were found to have CHD from 1.45 (rs10116277) to 4.77 (rs2383206) years earlier than those with the wild-type alleles.
|
21375403 |
2011 |
|
rs10118757
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association between rs10118757(A/G) in methylthioadenosine phosphorylase gene and coronary artery disease in Chinese Hans.
|
23462334 |
2013 |
|
rs10159239
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The Single Nucleotide Polymorphism rs10159239 was examined by logistic regression with known risk factors for Coronary artery disease and remained significant (0.035).
|
31639433 |
2020 |
|
rs1017
|
|
|
0.030 |
GeneticVariation |
BEFREE |
In conclusion, ISL1 common variant rs1017 is not associated with increased genetic risk of CHD in the white population.
|
23229290 |
2013 |
|
rs1017
|
|
|
0.030 |
GeneticVariation |
BEFREE |
This is the first study which indicates that ISL1 common variant rs1017 may not play a role in sporadic CHD susceptibility in the Chinese population.
|
22480195 |
2012 |
|
rs1017
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We concluded that rs1017 contributed to the risk of CHD in Chinese Han people, and ISL1 may be involved in the formation and development of the heart.
|
24634231 |
2014 |
|
rs10217586
|
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide association study of a coronary artery disease risk variant.
|
23364394 |
2013 |
|
rs10218795
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Two-marker association tests yield new disease associations for coronary artery disease and hypertension.
|
21626137 |
2011 |
|
rs10235849
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Among the 8 single nucleotide polymorphisms (SNPs) identified, six SNPs are in strong linkage disequilibrium and the minor alleles are associated with lower CHD risk (for rs10235849 chosen as tag SNP, p = 0.0069, OR (95% CI) = 0.68 (0.51-0.90)).
|
27034249 |
2016 |
|
rs1035071612
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The C766T low-density lipoprotein receptor related protein polymorphism and coronary artery disease, plasma lipoproteins, and longevity in the Czech population.
|
11357934 |
2001 |
|
rs1039659576
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Compound mutants for (MTHFD-G1958A, MTHFR-C677T and MTR-A2756G) and (MTHFD-G1958A, RFC1-G80A and MTR-A2756G) may increase the risk of CHD.
|
23701284 |
2013 |
|
rs1039659576
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Interestingly, all marginally significant SNPs in SLC19A1 are in strong linkage disequilibrium (r(2)> or = 0.8) with the nonsynonymous coding SNP rs1051266 (c.80A>G), which has previously been associated with nonsyndromic cases of CHD.
|
20718043 |
2010 |
|
rs10399931
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results do not support that rs10399931 is associated with clinical phenotypes of CHD and the extent of coronary lesions; however, YKL-40 levels are higher in CHD patients and associated with its clinical phenotypes.
|
22433444 |
2012 |
|
rs10401969
|
|
|
0.800 |
GeneticVariation |
GWASCAT |
Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
|
27790247 |
2016 |
|
rs10401969
|
|
|
0.800 |
GeneticVariation |
GWASDB |
Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.
|
21347282 |
2011 |
|
rs1041981
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The seven SNPs (including the rs909253 and rs1041981 SNPs previously implicated in the risk of CHD) were in strong linkage disequilibrium with each other and contributed to six common haplotypes.
|
16839190 |
2006 |
|
rs1042031
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The study was carried out to examine the association between apolipoprotein B (ApoB) EcoRI polymorphism (E<sup>-</sup> vs. E<sup>+</sup>) (rs1042031) and coronary heart disease (CHD) risk by systematically analyzing multiple independent studies.
|
27637205 |
2016 |
|
rs10420321
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Odds ratios (ORs) and 95 % confidence intervals (95 % CIs) were used to assess the strength of the association. rs16999593 was associated with the CHD under the heterozygous (CT vs TT: OR 0.62; 95 % CI 0.41-0.95; p = 0.03), dominant (CT + CC vs TT: OR 0.63; 95 % CI 0.42-0.95; p = 0.03), and allele models (C vs T: OR 0.07; 95 % CI 0.50-1.00; p = 0.05). rs2228612 was related with the CHD under the heterozygous (AG vs AA: OR 0.42; 95 % CI 0.27-0.65; p = 0.0001), homozygous (GG vs AA: OR 0.43; 95 % CI 0.240-0.77; p = 0.004), dominant (AG + GG vs AA: OR 0.42; 95 % CI 0.28-0.64; p < 0.0001), and allele models (G vs A: OR 0.62; 95 % CI 0.47-0.82; p = 0.0007). rs10420321 correlated with the CHD only under the recessive model (GG vs AG + AA: OR 0.61; 95 % CI 0.37-1.01, p = 0.05).
|
25596970 |
2015 |
|
rs1042522
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The Arg72 variant of the p53 functional polymorphism (rs1042522) is associated with coronary artery disease in young South Africans of Indian ancestry.
|
27436625 |
2016 |
|
rs1042579
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The TM A455V polymorphism predicts risk of developing CHD in blacks.
|
11245641 |
2001 |