Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1333049
rs1333049
0.900 GeneticVariation BEFREE This study confirms the association between 9p21 (rs1333049) and fatal CHD in a Norwegian population-based cohort. 24728607

2014

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation BEFREE Our case-control study and meta-analysis suggest that rs1333049 is a useful risk marker of CHD. 24930384

2014

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation BEFREE Association Study Between Coronary Artery Disease and rs1333049 Polymorphism at 9p21.3 Locus in Italian Population. 28639227

2017

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation BEFREE ANRIL polymorphisms (rs1333049 and rs3217992) in relation to plasma CRP levels among in-patients with CHD. 31770616

2020

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation BEFREE The leading coronary artery disease-associated SNP rs1333049 was associated with coronary artery disease; however, none of the 9p21 SNP evaluated in the present study were associated with extreme longevity. 25257646

2015

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation GWASDB Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. 21347282

2011

dbSNP: rs1333049
rs1333049
C 0.900 GeneticVariation GWASCAT A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease. 21606135

2011

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation GWASDB A genome-wide association study for coronary artery disease identifies a novel susceptibility locus in the major histocompatibility complex. 22319020

2012

dbSNP: rs1333049
rs1333049
C 0.900 GeneticVariation GWASCAT Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants. 24262325

2014

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation BEFREE We genotyped the rs1333049 single-nucleotide polymorphism in 593 Caucasian individuals with stable coronary artery disease recruited in the Heart and Soul Study. 19171343

2009

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation GWASCAT Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases. 27790247

2016

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation BEFREE Recent genetic studies identified the rs1333049 variant on chromosome 9p21 as a major susceptibility locus for coronary artery disease and myocardial infarction (MI). 20231156

2010

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation GWASDB A genome-wide association study of a coronary artery disease risk variant. 23364394

2013

dbSNP: rs1333049
rs1333049
C 0.900 GeneticVariation GWASDB Of thousands of chromosomal loci studied, the same locus had the strongest association with coronary artery disease in both the WTCCC and the German studies: chromosome 9p21.3 (SNP, rs1333049) (P=1.80x10(-14) and P=3.40x10(-6), respectively). 17634449

2007

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation GWASDB Two-marker association tests yield new disease associations for coronary artery disease and hypertension. 21626137

2011

dbSNP: rs1333049
rs1333049
C 0.900 GeneticVariation GWASDB Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. 17554300

2007

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation BEFREE Independent association of the variant rs1333049 at the 9p21 locus and coronary heart disease. 21874923

2011

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation BEFREE The results showed that 3 SNPs in whites (rs599839, rs1333049, and rs501120; HRRs were 1.10 (P = 0.044), 1.14 (P < 0.001), and 1.14 (P = 0.030), respectively) and 1 SNP in African Americans (rs7250581; HRR = 1.60, P = 0.05) were significantly associated with incident CHD. 19955471

2010

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation BEFREE Using the combined TDT/S-TDT test, the 3 single nucleotide polymorphisms (SNP), rs10757274, rs2383206 and rs1333049, were strongly associated with early-onset CHD (p = 2.7 x 10(-6), 2.7 x 10(-6), 3.8 x 10(-7), respectively). 18957718

2008

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation BEFREE SNP rs1333049 on chromosome 9p21.3 was associated with both CHD and stroke (HR=1.20, 95% CI 1.08-1.34 for incident CHD events and 1.15, 0.99-1.34 for incident stroke). 18979498

2009

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation BEFREE However, the effect of rs1333049 on clinical outcomes in patients with established coronary disease has yet to be determined. 20400779

2010

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation BEFREE Our study aims to explore the association of rs7025486 single-nucleotide polymorphisms (SNP) in DAB2IP and rs1333049 on chromosome 9p21.3 with the coronary artery disease in Chinese population. 28962556

2017

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation BEFREE Despite excellent power, the 9p21 locus SNP (rs1333049) was only modestly associated with MI (HR = 1.09, p-value = 0.02) and marginally with CHD (HR = 1.06, p-value = 0.08). 26950853

2016

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation BEFREE To address the relationship of rs1333049, the 9p21 variant showing the strongest association with coronary heart disease (CHD), with carotid plaques and plaque-free common carotid artery intima-media thickness (CCA-IMT) in older adults from 2 French population-based cohorts. 22436605

2012

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation BEFREE Of thousands of chromosomal loci studied, the same locus had the strongest association with coronary artery disease in both the WTCCC and the German studies: chromosome 9p21.3 (SNP, rs1333049) (P=1.80x10(-14) and P=3.40x10(-6), respectively). 17634449

2007