Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.090 | GeneticVariation | BEFREE | The potential interaction between PPARG2 P12A, overweight, and increased CHD risk needs further evaluation. | 15920035 | 2005 |
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0.090 | GeneticVariation | BEFREE | But PPARG P12A polymorphism is not associated with CHD risk. | 22987045 | 2012 |
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0.090 | GeneticVariation | BEFREE | The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor gamma-2 gene (PPARγ2) is associated with increased risk of coronary artery disease: a meta-analysis. | 23300871 | 2012 |
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0.090 | GeneticVariation | BEFREE | Our results suggest that the Pro12Ala, C161T and C1431T polymorphisms of PPARG gene are not associated with CHD susceptibility. | 23065280 | 2013 |
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0.090 | GeneticVariation | BEFREE | The aim was to investigate if the polymorphism PPARgamma2 Pro12Ala, which encodes a less efficient transcription factor, was associated with risk of acute coronary disease and if there were interactions between this polymorphism and factors that modify PPARgamma activity, such as alcohol intake, smoking, and use of non-steroidal anti-inflammatory medicine. | 19500413 | 2009 |
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0.090 | GeneticVariation | BEFREE | Homozygosity for the Ala allele of the PPARγ2 Pro12Ala polymorphism is associated with reduced risk of coronary artery disease. | 21206011 | 2010 |
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0.090 | GeneticVariation | BEFREE | No association of Pro12Ala polymorphism of PPAR-gamma gene with coronary artery disease in Korean subjects. | 17322631 | 2007 |
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0.090 | GeneticVariation | BEFREE | Association of the PPARG Pro12Ala polymorphism with type 2 diabetes and incident coronary heart disease in a Hong Kong Chinese population. | 22515931 | 2012 |
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0.090 | GeneticVariation | BEFREE | Our findings shows the association of these two polymorphisms with serum triglyceride levels, which was increased in the order of P12P-CC < P12P-CT < P12A-CC < P12A-CT in the CHD patients with diabetes. | 21833536 | 2011 |