Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1333049
rs1333049
0.900 GeneticVariation BEFREE ANRIL polymorphisms (rs1333049 and rs3217992) in relation to plasma CRP levels among in-patients with CHD. 31770616

2020

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation BEFREE Gender-based subgroup tests showed that four polymorphisms (rs75227345, rs2383205, rs10738606 and rs1333049) were associated with CHD in males (p < .05). 31496134

2019

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation BEFREE Association Study Between Coronary Artery Disease and rs1333049 Polymorphism at 9p21.3 Locus in Italian Population. 28639227

2017

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation BEFREE Our study aims to explore the association of rs7025486 single-nucleotide polymorphisms (SNP) in DAB2IP and rs1333049 on chromosome 9p21.3 with the coronary artery disease in Chinese population. 28962556

2017

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation GWASCAT Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases. 27790247

2016

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation BEFREE Despite excellent power, the 9p21 locus SNP (rs1333049) was only modestly associated with MI (HR = 1.09, p-value = 0.02) and marginally with CHD (HR = 1.06, p-value = 0.08). 26950853

2016

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation BEFREE The leading coronary artery disease-associated SNP rs1333049 was associated with coronary artery disease; however, none of the 9p21 SNP evaluated in the present study were associated with extreme longevity. 25257646

2015

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation BEFREE This study confirms the association between 9p21 (rs1333049) and fatal CHD in a Norwegian population-based cohort. 24728607

2014

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation BEFREE Our case-control study and meta-analysis suggest that rs1333049 is a useful risk marker of CHD. 24930384

2014

dbSNP: rs1333049
rs1333049
C 0.900 GeneticVariation GWASCAT Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants. 24262325

2014

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation GWASDB A genome-wide association study of a coronary artery disease risk variant. 23364394

2013

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation GWASDB A genome-wide association study for coronary artery disease identifies a novel susceptibility locus in the major histocompatibility complex. 22319020

2012

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation BEFREE To address the relationship of rs1333049, the 9p21 variant showing the strongest association with coronary heart disease (CHD), with carotid plaques and plaque-free common carotid artery intima-media thickness (CCA-IMT) in older adults from 2 French population-based cohorts. 22436605

2012

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation BEFREE The Ch9p21 SNPs rs1333049 (OR 1.17; 95% confidence limits 1.11-1.24) and rs10757274 (OR 1.17; 1.09-1.26), MIA3 rs17465637 (OR 1.10; 1.04-1.15), Ch2q36 rs2943634 (OR 1.08; 1.03-1.14), APC rs383830 (OR 1.10; 1.02, 1.18), MTHFD1L rs6922269 (OR 1.10; 1.03, 1.16), CXCL12 rs501120 (OR 1.12; 1.04, 1.20), and SMAD3 rs17228212 (OR 1.11; 1.05, 1.17) were all associated with CHD risk, but not with the CHD biomarkers and risk factors measured. 21804106

2012

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation GWASDB Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease. 22751097

2012

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation GWASDB Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. 21347282

2011

dbSNP: rs1333049
rs1333049
C 0.900 GeneticVariation GWASCAT A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease. 21606135

2011

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation GWASDB Two-marker association tests yield new disease associations for coronary artery disease and hypertension. 21626137

2011

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation BEFREE Independent association of the variant rs1333049 at the 9p21 locus and coronary heart disease. 21874923

2011

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation GWASDB Large-scale gene-centric analysis identifies novel variants for coronary artery disease. 21966275

2011

dbSNP: rs1333049
rs1333049
C 0.900 GeneticVariation GWASDB A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease. 21606135

2011

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation BEFREE Recent genetic studies identified the rs1333049 variant on chromosome 9p21 as a major susceptibility locus for coronary artery disease and myocardial infarction (MI). 20231156

2010

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation BEFREE The results showed that 3 SNPs in whites (rs599839, rs1333049, and rs501120; HRRs were 1.10 (P = 0.044), 1.14 (P < 0.001), and 1.14 (P = 0.030), respectively) and 1 SNP in African Americans (rs7250581; HRR = 1.60, P = 0.05) were significantly associated with incident CHD. 19955471

2010

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation BEFREE However, the effect of rs1333049 on clinical outcomes in patients with established coronary disease has yet to be determined. 20400779

2010

dbSNP: rs1333049
rs1333049
0.900 GeneticVariation BEFREE We genotyped the rs1333049 single-nucleotide polymorphism in 593 Caucasian individuals with stable coronary artery disease recruited in the Heart and Soul Study. 19171343

2009