Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.080 | GeneticVariation | BEFREE | The present meta-analysis suggests that the TLR4 Asp299Gly polymorphism was not associated with decreased CHD risk in Caucasians. | 28793055 | 2017 |
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0.080 | GeneticVariation | BEFREE | TLR4 gene polymorphism (Asp299Gly) attenuates innate immune responsiveness, reduces the risk for coronary artery disease, and increases a chance of longevity. | 19273219 | 2009 |
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0.080 | GeneticVariation | BEFREE | We studied the TLR4 gene Asp299Gly polymorphism in relation to susceptibility to myocardial infarction in a cohort of patients with angiographically documented coronary artery disease, and performed a meta-analysis using data sets from three independent studies. | 15864121 | 2005 |
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|
0.080 | GeneticVariation | BEFREE | A polymorphism of the TLR4 gene, Asp299Gly, is associated with an increased risk for coronary heart diseases in Caucasian populations. | 15910856 | 2005 |
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0.080 | GeneticVariation | BEFREE | The TLR4/Asp299Gly and CD14/C-260T polymorphisms and plasma sCD14 concentrations do not appear as significant predictors of the risk of CHD in healthy individuals. | 15367917 | 2004 |
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|
0.080 | GeneticVariation | BEFREE | Toll-like receptor 4 gene Asp299Gly polymorphism is associated with reductions in vascular inflammation, angiographic coronary artery disease, and clinical diabetes. | 15632890 | 2004 |
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0.080 | GeneticVariation | BEFREE | Among symptomatic men with documented coronary artery disease, the TLR4 Asp299Gly polymorphism was associated with the risk of cardiovascular events. | 12742999 | 2003 |
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0.080 | GeneticVariation | BEFREE | The findings of this study do not support the hypothesis that the TLR4 Asp299Gly polymorphism influences predisposition to and progression of coronary artery disease. | 12957699 | 2003 |