Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs671
rs671
0.900 GeneticVariation BEFREE Aldehyde dehydrogenase 2 (ALDH2) rs671 polymorphism is an established genetic risk of hypertension, diabetes, and coronary heart diseases in Asian population. 30846829

2020

dbSNP: rs671
rs671
0.900 GeneticVariation BEFREE Six common variants at ALDH2 gene, including rs2339840, rs4648328, rs4767939, rs11066028, rs16941669, and rs671, were selected to test the associations of those polymorphisms with the cardiovascular outcome in patients with CHD after PCI. 29742731

2018

dbSNP: rs671
rs671
0.900 GeneticVariation BEFREE Interactions between ALDH2 rs671 polymorphism and lifestyle behaviors on coronary artery disease risk in a Chinese Han population with dyslipidemia: A guide to targeted heart health management. 29960587

2018

dbSNP: rs671
rs671
0.900 GeneticVariation BEFREE Previous studies demonstrated that aldehyde dehydrogenase 2 (ALDH2) rs671 polymorphism, which eliminates ALDH2 activity down to 1%-6%, is a susceptibility gene for coronary disease. 27191745

2016

dbSNP: rs671
rs671
0.900 GeneticVariation BEFREE We genotyped rs671 of ALDH2 in 96 coronary heart disease (CHD) patients with four methods including high resolution melting analysis (HRM), TaqMan allelic discrimination assay (TaqMan), allele-specific PCR (AS-PCR) and pyrosequencing. 25803854

2015

dbSNP: rs671
rs671
0.900 GeneticVariation BEFREE The association between the aldehyde dehydrogenase 2 (ALDH2, rs671) genotypes and the estimated glomerular filtration rate (eGFR) was investigated in Japanese hypertensive patients with/without coronary artery disease or with ischemic heart failure (HF), and age/sex-matched normotensive healthy controls. 24067347

2014

dbSNP: rs671
rs671
0.900 GeneticVariation BEFREE ALDH2 Glu504Lys polymorphism and susceptibility to coronary artery disease and myocardial infarction in East Asians: a meta-analysis. 24333098

2014

dbSNP: rs671
rs671
0.900 GeneticVariation BEFREE The Glu504Lys polymorphism of aldehyde dehydrogenase 2 contributes to development of coronary artery disease. 25263942

2014

dbSNP: rs671
rs671
0.900 GeneticVariation BEFREE Our meta-analysis results showed that the A variant of the ALDH2 rs671 polymorphism may be associated with increase risks of CHD (odds ratios [OR]=1.36, 95% confidence interval [CI]=1.06-1.75, p=0.017) and MI (OR=1.64, 95% CI=1.22-2.20, p=0.001). 23697560

2013

dbSNP: rs671
rs671
A 0.900 GeneticVariation GWASCAT Genome-wide association study of coronary artery disease in the Japanese. 21971053

2012

dbSNP: rs671
rs671
A 0.900 GeneticVariation GWASDB Genome-wide association study of coronary artery disease in the Japanese. 21971053

2012

dbSNP: rs671
rs671
0.900 GeneticVariation BEFREE The ALDH2 Glu504Lys polymorphism is associated with coronary artery disease in Han Chinese: Relation with endothelial ADMA levels. 20417517

2010