rs145922845
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The interleukin-10 Gly15Arg mutation is rare in patients with Crohn's disease, and is not associated with the disease in the Netherlands.
|
15843082 |
2005 |
rs145922845
|
|
|
0.030 |
GeneticVariation |
BEFREE |
A Gly15Arg mutation in the leader sequence of IL-10 was found in a multiple CD-affected family.
|
12825869 |
2003 |
rs145922845
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Screening of the coding region of the IL-10 gene by polymerase chain reaction--single strand conformation polymorphism (PCR-SSCP) analysis revealed a rare sequence variation in exon 1 leading to an amino acid exchange (G-->A; G15R) in two patients with CD and five healthy controls.
|
11271474 |
2000 |
rs1800871
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Single nucleotide polymorphisms (SNPs) that affect IL-10 production, such as rs1800896 (G/A) at position -1082 and rs1800871 (C/T) at position -819 in the promoter region of the IL10 gene, have been associated with CD and/or UC, but the results were inconsistent.
|
27558476 |
2016 |
rs1800871
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Of the five IL-10 tag-SNPs, rs2222202 (C/T) (P = 0.03) and rs1800871 (C/T) (P = 0.05) showed significant allelic associations with CD.
|
19210299 |
2009 |
rs1800896
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Single nucleotide polymorphisms (SNPs) that affect IL-10 production, such as rs1800896 (G/A) at position -1082 and rs1800871 (C/T) at position -819 in the promoter region of the IL10 gene, have been associated with CD and/or UC, but the results were inconsistent.
|
27558476 |
2016 |
rs1800896
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We demonstrated an association with CD for SNPs rs3024505 and rs1800896, and phenotypic analysis indicated an association of rs3024505 with an early age at first diagnosis, stricturing CD behavior, and requirement for bowel resection.
|
21354456 |
2011 |
rs2222202
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Of the five IL-10 tag-SNPs, rs2222202 (C/T) (P = 0.03) and rs1800871 (C/T) (P = 0.05) showed significant allelic associations with CD.
|
19210299 |
2009 |
rs3024493
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
|
26974007 |
2016 |