| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.850 | GeneticVariation | BEFREE | For example, we characterized that the Crohn's disease risk variant for rs3810936 increases NFKB1 binding and results in altered gene expression. | 30254052 | 2018 |
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|
0.850 | GeneticVariation | BEFREE | Our analysis suggested that rs3810936 polymorphism was significantly associated with decreased risk of Crohn's disease (CD) and ulcerative colitis (UC). | 29873318 | 2018 |
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|
0.850 | GeneticVariation | BEFREE | Our results confirmed a significant association of CD with the following previously reported risk loci: rs3810936 in TNFSF15 (OR=1.83, p<2.2×10(-16)), rs76418789 in IL23R (OR=0.47, p=1.14×10(-8)) and rs2241880 in ATG16L1 (OR=1.30, p=5.28×10(-6)). | 25731871 | 2016 |
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|
0.850 | GeneticVariation | BEFREE | The minor T alleles and the TT genotypes of rs10114470 and rs3810936 were significantly protectively associated with both CD and UC. | 25501099 | 2014 |
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|
0.850 | GeneticVariation | BEFREE | According to the subgroup analysis by ethnicity, except for rs4263839 in Caucasian and rs4979462 in Asian, all the rest investigated TNFSF15 polymorphisms were associated with CD risk and rs3810936 and rs7848647 polymorphism in Asian as well as rs6478108 polymorphism in Caucasian were associated with UC risk. | 25028192 | 2014 |
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|
C | 0.850 | GeneticVariation | GWASDB | Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. | 21102463 | 2010 |
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|
C | 0.850 | GeneticVariation | GWASCAT | Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. | 21102463 | 2010 |
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|
0.850 | GeneticVariation | GWASDB | Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease. | 16221758 | 2005 |