|
rs6478108
|
|
|
0.760 |
GeneticVariation |
BEFREE |
For rs6478108 polymorphism, we also detected a significantly protective association with CD risk in all genetic model but not in UC.
|
29873318 |
2018 |
|
rs6478108
|
|
|
0.760 |
GeneticVariation |
BEFREE |
Using genetic data from published studies on CD, PBC and leprosy we revealed that bearing a T allele at rs6478108/rs6478109 (r(2) = 1) or rs4979462 was significantly associated with increased risk of CD and decreased risk of leprosy, while the T allele at rs4979462 was associated with significantly increased risk of PBC.
|
27507062 |
2016 |
|
rs6478108
|
|
|
0.760 |
GeneticVariation |
BEFREE |
The CC genotype of rs6478108, AA genotype of rs4263839, the AA genotype of rs6478109, the TT genotype of rs7848647 and the CC genotype of rs7869487 were all protectively associated with CD but not with UC.
|
25501099 |
2014 |
|
rs6478108
|
|
|
0.760 |
GeneticVariation |
BEFREE |
According to the subgroup analysis by ethnicity, except for rs4263839 in Caucasian and rs4979462 in Asian, all the rest investigated TNFSF15 polymorphisms were associated with C</span>D risk and rs3810936 and rs7848647 polymorphism in Asian as well as rs6478108 polymorphism in Caucasian were associated with UC risk.
|
25028192 |
2014 |
|
rs6478108
|
|
|
0.760 |
GeneticVariation |
GWASDB |
A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.
|
23266558 |
2013 |
|
rs6478108
|
|
|
0.760 |
GeneticVariation |
BEFREE |
A total of 666 IBD families (corresponding to 2,982 relatives) with European ancestry were genotyped for the rs6478108 and rs7869487 polymorphisms, which define the main TNFSF15 haplotypes previously associated with CD.
|
19174806 |
2009 |
|
rs6478108
|
|
|
0.760 |
GeneticVariation |
BEFREE |
Carriers of three polymorphisms, including rs3810936, rs6478108, and rs7848647, showed statistically significant association with CD (adjusted OR [aOR] 2.81, 95% confidence interval [CI] 1.94-4.07, P= 4.4 x 10(-8); aOR 3.49, 95% CI 2.42-5.04, P= 2.7 x 10(-11); and aOR 3.49, 95% CI 2.42-5.03, P= 2.2 x 10(-11), respectively).
|
18422820 |
2008 |
|
rs6478108
|
|
|
0.760 |
GeneticVariation |
GWASDB |
Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease.
|
16221758 |
2005 |