|
rs7517847
|
|
|
0.880 |
GeneticVariation |
BEFREE |
A significantly increased risk of CD early onset was observed in Poles carrying at least one rs7517847: G allele.
|
31052515 |
2019 |
|
rs7517847
|
|
|
0.880 |
GeneticVariation |
GWASCAT |
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
|
26974007 |
2016 |
|
rs7517847
|
|
|
0.880 |
GeneticVariation |
BEFREE |
Overall, a significant association was found between all CD and the rs7517847 polymorphism (OR = 0.699, 95% CI = 0.659 ~ 0.741, P < 0.001).
|
26678098 |
2015 |
|
rs7517847
|
|
|
0.880 |
GeneticVariation |
BEFREE |
OR = 1.409, 95% CI 1.279, 1.552).In conclusion, this meta-analysis demonstrates that rs7517847 is associated with the risk of CD in Caucasians.
|
26090488 |
2015 |
|
rs7517847
|
|
A |
0.880 |
GeneticVariation |
GWASCAT |
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.
|
26192919 |
2015 |
|
rs7517847
|
|
|
0.880 |
GeneticVariation |
BEFREE |
Rs1884444 was found to confer risk for UC and psoriasis, rs10889677 for CD and psoriasis, while rs2201841 and rs7517847 had effect only in CD.
|
23093364 |
2013 |
|
rs7517847
|
|
|
0.880 |
GeneticVariation |
BEFREE |
The present study confirms the association of the heterozygous and homozygous IL23R rs7517847 variant with CD and suggests an additive effect of smoking to the ATG16L1 rs2241879 C risk allele SNP, in the context of the multifactorial model established for the development of CD and a protective effect of the same allele against extra-intestinal manifestations.
|
21206965 |
2011 |
|
rs7517847
|
|
|
0.880 |
GeneticVariation |
BEFREE |
The rs7517847 variant, in contrast, was associated neither with CD nor with UC.
|
20192940 |
2010 |
|
rs7517847
|
|
|
0.880 |
GeneticVariation |
BEFREE |
Our meta-analysis supports that two polymorphisms (Arg381Gln and rs7517847) within the IL-23R gene may be considered to be protective factors against developing CD.
|
20157760 |
2010 |
|
rs7517847
|
|
|
0.880 |
GeneticVariation |
BEFREE |
The data show an association of both IL23R SNPs with overall IBD (statistically stronger, rs7517847; odds ratio [OR] = 0.79, 95% confidence interval [CI]: 0.67-0.94, minor allele frequencies: 0.355 in IBD patients versus 0.410 in controls; P = 0.005), somewhat stronger in Crohn's disease (OR = 0.74, 95% CI: 0.61-0.91) than in ulcerative colitis (OR = 0.84, 95% CI: 0.69-1.03).
|
18383521 |
2008 |
|
rs7517847
|
|
|
0.880 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis.
|
17435756 |
2007 |
|
rs7517847
|
|
|
0.880 |
GeneticVariation |
GWASCAT |
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis.
|
17435756 |
2007 |