Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs5743708
rs5743708
TLR2
0.060 GeneticVariation BEFREE The TLR2-Arg753Gln SNP was genotyped in 181 patients after bone marrow transplantation: 83 and 98 patients with and without CMV infection, respectively. 31656159

2019
dbSNP: rs5743708
rs5743708
TLR2
0.060 GeneticVariation BEFREE Among various TLR2, TLR4 and TLR9 polymorphisms, TLR2 2258 G>A SNP seems to be an important factor associated with increased risk of congenital HCMV infection in Polish fetuses and neonates. 28118851

2017
dbSNP: rs5743708
rs5743708
TLR2
0.060 GeneticVariation BEFREE The inconsistent observations of the immunological and clinical significance of the TLR2 R753Q polymorphism for CMV infection indicates the influence of confounders. 27723526

2016
dbSNP: rs5743708
rs5743708
TLR2
0.060 GeneticVariation BEFREE Relationship between toll-like receptor 2 Arg677Trp and Arg753Gln and toll-like receptor 4 Asp299Gly polymorphisms and cytomegalovirus infection. 24813591

2014
dbSNP: rs5743708
rs5743708
TLR2
0.060 GeneticVariation BEFREE In conclusion, homozygosity for TLR2 R753Q SNP is a marker for CMV disease risk, especially for tissue-invasive disease, after liver transplantation. 22219347

2012
dbSNP: rs5743708
rs5743708
TLR2
0.060 GeneticVariation BEFREE A multivariate Cox proportional hazard model demonstrated a trend towards a higher risk of CMV disease among patients who were homozygous for the TLR2 Arg753Gln polymorphism (hazard ratio, 1.91 [95% confidence interval, 0.91-3.40]; P=.08) after adjusting for patient age, CMV serostatus, and allograft rejection. 17443468

2007