Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1555745467
rs1555745467
A 0.700 GeneticVariation CLINVAR

dbSNP: rs367814475
rs367814475
IVD
T 0.700 CausalMutation CLINVAR

dbSNP: rs67376798
rs67376798
0.010 GeneticVariation BEFREE The DPYD*2A variant statistically significantly associated with the specific AEs nausea/vomiting (P = .007) and neutropenia (P < .001), whereas D949V statistically significantly associated with dehydration (P = .02), diarrhea (P = .003), leukopenia (P = .002), neutropenia (P < .001), and thrombocytopenia (P < .001). 25381393

2014

dbSNP: rs267606694
rs267606694
0.010 GeneticVariation BEFREE CA12 stands out since the CA12(E143K) mutation causes salt wasting in sweat and dehydration in humans. 26486891

2015

dbSNP: rs202166715
rs202166715
0.010 GeneticVariation BEFREE The clinical and diagnostic course of an infant with recurrent episodes of watery diarrhea and hypernatremic dehydration found to be homozygous for a rare variant in the SLC5A1 gene, c.187C>T (p.R63X) is described. 28283348

2018

dbSNP: rs1057519076
rs1057519076
0.010 GeneticVariation BEFREE Erythrocyte ion content and dehydration modulate maximal Gardos channel activity in KCNN4 V282M/+ hereditary xerocytosis red cells. 31091145

2019