|
rs4804803
|
|
|
0.070 |
GeneticVariation |
BEFREE |
A common CD209-336G/A (rs4804803) polymorphism in DC-SIGN may affect severity of dengue virus infection (DEN) and incidence of dengue fever (DF) or the more severe dengue hemorrhagic fever (DHF).
|
29054571 |
2018 |
|
rs4804803
|
|
|
0.070 |
GeneticVariation |
BEFREE |
A single nucleotide polymorphism (SNP) in the promoter region of CD209 (-336 A/G; rs4804803) affects transcription and is associated with the severity of tuberculosis and dengue fever.
|
20470843 |
2010 |
|
rs1801274
|
|
|
0.020 |
GeneticVariation |
BEFREE |
A single-nucleotide polymorphism in FcγRIIa (rs1801274) results in altered affinity of the receptor for different subclasses of immunoglobulin G, and is a key player in determining the susceptibility to or protection from severe clinical infection of dengue.
|
26240159 |
2015 |
|
rs1285933
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of rs1285933 single nucleotide polymorphism in CLEC5A gene with dengue severity and its functional effects.
|
28764923 |
2017 |
|
rs4804803
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Because the -336A/G SNP (rs4804803) polymorphism in the promoter of CD209 modulates DC-SIGN expression, we investigated the putative association of this polymorphism with DENV infection and its pathogenesis.
|
24797508 |
2014 |
|
rs1799983
|
|
|
0.010 |
GeneticVariation |
BEFREE |
For the ENOS (rs1799983) SNP, the genotype GT was positively associated with protection for development of the clinical form in DHF compared to dengue fever (OR = 0.39, 95% CI = (0.13-1.14), p = 0.0058) in codominant GG/GT/TT and overdominant model GT vs GG + TT (OR = 0.35, 95% CI = (0.12-1.02), p = 0.04).
|
30452889 |
2019 |
|
rs763780
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Frequency of T/C genotype of IL17F rs763780 was significantly lower in DEN group as compared to HC [P=0.033, OR with 95% CI 0.43 (0.19-0.95)].
|
25890879 |
2015 |
|
rs1800629
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Higher frequency of rs1800629 'G/A' genotype was observed in DHF cases as compared to DF cases.
|
23380141 |
2013 |
|
rs12252
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In naturally occurring, genetic loss-of-function studies, MKs from healthy subjects harboring a homozygous mutation in IFITM3 (rs12252-C, a common single-nucleotide polymorphism in areas of the world where DENV is endemic) were significantly more susceptible to DENV infection.
|
30723081 |
2019 |
|
rs1801274
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In this study, real-time PCR was used to characterize the distribution of rs1801274 and rs4804803 in subjects with asymptomatic dengue infection (n=145), uncomplicated dengue (n=67), and severe dengue (n=36) in Morelos.
|
24911936 |
2014 |
|
rs4804803
|
|
|
0.070 |
GeneticVariation |
BEFREE |
In this study, real-time PCR was used to characterize the distribution of rs1801274 and rs4804803 in subjects with asymptomatic dengue infection (n=145), uncomplicated dengue (n=67), and severe dengue (n=36) in Morelos.
|
24911936 |
2014 |
|
rs1131454
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Polymorphisms in the OAS1 (rs1131454 and rs10774671), OAS3 (rs2285932 and rs2072136) and OAS2 (rs15895 and rs1732778) genes were studied using PCR followed by restriction fragment length polymorphism methods in 109 patients hospitalized for dengue (DEN) and 105 healthy controls (HCs) who have no documented evidence of symptomatic dengue.
|
23337612 |
2013 |
|
rs10774671
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Polymorphisms in the OAS1 (rs1131454 and rs10774671), OAS3 (rs2285932 and rs2072136) and OAS2 (rs15895 and rs1732778) genes were studied using PCR followed by restriction fragment length polymorphism methods in 109 patients hospitalized for dengue (DEN) and 105 healthy controls (HCs) who have no documented evidence of symptomatic dengue.
|
23337612 |
2013 |
|
rs2285932
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Polymorphisms in the OAS1 (rs1131454 and rs10774671), OAS3 (rs2285932 and rs2072136) and OAS2 (rs15895 and rs1732778) genes were studied using PCR followed by restriction fragment length polymorphism methods in 109 patients hospitalized for dengue (DEN) and 105 healthy controls (HCs) who have no documented evidence of symptomatic dengue.
|
23337612 |
2013 |
|
rs2072136
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Polymorphisms in the OAS1 (rs1131454 and rs10774671), OAS3 (rs2285932 and rs2072136) and OAS2 (rs15895 and rs1732778) genes were studied using PCR followed by restriction fragment length polymorphism methods in 109 patients hospitalized for dengue (DEN) and 105 healthy controls (HCs) who have no documented evidence of symptomatic dengue.
|
23337612 |
2013 |
|
rs15895
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Polymorphisms in the OAS1 (rs1131454 and rs10774671), OAS3 (rs2285932 and rs2072136) and OAS2 (rs15895 and rs1732778) genes were studied using PCR followed by restriction fragment length polymorphism methods in 109 patients hospitalized for dengue (DEN) and 105 healthy controls (HCs) who have no documented evidence of symptomatic dengue.
|
23337612 |
2013 |
|
rs1732778
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Polymorphisms in the OAS1 (rs1131454 and rs10774671), OAS3 (rs2285932 and rs2072136) and OAS2 (rs15895 and rs1732778) genes were studied using PCR followed by restriction fragment length polymorphism methods in 109 patients hospitalized for dengue (DEN) and 105 healthy controls (HCs) who have no documented evidence of symptomatic dengue.
|
23337612 |
2013 |
|
rs1732778
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Polymorphisms in the OAS1 SNPs (rs1131454), OAS2 SNPs (rs1293762, rs15895 and rs1732778) and OAS3 SNPs (rs2285932 and rs2072136) genes were studied using PCR followed by restriction fragment length polymorphism methods in 30 patients for dengue infection and 40 control group who have no documented evidence of symptomatic dengue.
|
24819159 |
2015 |
|
rs2072136
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Polymorphisms in the OAS1 SNPs (rs1131454), OAS2 SNPs (rs1293762, rs15895 and rs1732778) and OAS3 SNPs (rs2285932 and rs2072136) genes were studied using PCR followed by restriction fragment length polymorphism methods in 30 patients for dengue infection and 40 control group who have no documented evidence of symptomatic dengue.
|
24819159 |
2015 |
|
rs4804803
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Polymorphisms in the promoter region of CD209 gene (rs735239, rs4804803, rs2287886) were investigated in 112 hospitalized cases of dengue (DEN) and 104 healthy controls to find out whether they are associated with dengue in a Western Indian population.
|
23624202 |
2013 |
|
rs1143627
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Polymorphisms of IL1B -31C/T (rs1143627) and IL1RA 86-base-pair tandem repeat were analyzed in 871 patients (DF = 384, DHF = 413, and DSS = 74).
|
24446526 |
2014 |
|
rs4804803
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Previously the severity and outcome of dengue fever and hepatitis C (diseases caused by viruses from the family Flaviviridae) were associated with the rs4804803 single nucleotide polymorphism (SNP) located in the promoter region of the human CD209 gene.
|
22061615 |
2012 |
|
rs2287886
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Results revealed a significantly higher frequency of 'G' allele and 'G/G' genotype of rs2287886 and A-A-G haplotype of CD209 gene in DEN compared to healthy controls [For 'G/G' genotype, P=0.0072, Odds ratio (OR) 2.43; For A-A-G haplotype, P=0.0033, OR 2].
|
23624202 |
2013 |
|
rs3775291
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Results revealed significantly lower frequency of TLR3 rs3775291 T allele [DHF vs. DF P = 0.015 odds ratio (OR) with 95% confidence interval (CI) 0.390 (0.160–0.880); DHF vs. HC P = 0.018 OR with 95% CI 0.410 (0.170–0.900)] and ‘T’ allele carriers [DHF vs. DF P = 0.008 OR with 95% CI 0.288 (0.115–0.722); DHF vs. HC P = 0.040 OR with 95% CI 0.393 (0.162–0.956)] and higher frequency of TIRAP rs8177374 ‘C/T’ genotype [DHF vs. HC P = 0.020 OR with 95% CI 2.643 (1.167–5.986)] in DHF.
|
25446400 |
2015 |
|
rs8177374
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Results revealed significantly lower frequency of TLR3 rs3775291 T allele [DHF vs. DF P = 0.015 odds ratio (OR) with 95% confidence interval (CI) 0.390 (0.160–0.880); DHF vs. HC P = 0.018 OR with 95% CI 0.410 (0.170–0.900)] and ‘T’ allele carriers [DHF vs. DF P = 0.008 OR with 95% CI 0.288 (0.115–0.722); DHF vs. HC P = 0.040 OR with 95% CI 0.393 (0.162–0.956)] and higher frequency of TIRAP rs8177374 ‘C/T’ genotype [DHF vs. HC P = 0.020 OR with 95% CI 2.643 (1.167–5.986)] in DHF.
|
25446400 |
2015 |