Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4804803
rs4804803
0.070 GeneticVariation BEFREE A common CD209-336G/A (rs4804803) polymorphism in DC-SIGN may affect severity of dengue virus infection (DEN) and incidence of dengue fever (DF) or the more severe dengue hemorrhagic fever (DHF). 29054571

2018

dbSNP: rs4804803
rs4804803
0.070 GeneticVariation BEFREE Because the -336A/G SNP (rs4804803) polymorphism in the promoter of CD209 modulates DC-SIGN expression, we investigated the putative association of this polymorphism with DENV infection and its pathogenesis. 24797508

2014

dbSNP: rs4804803
rs4804803
0.070 GeneticVariation BEFREE In this study, real-time PCR was used to characterize the distribution of rs1801274 and rs4804803 in subjects with asymptomatic dengue infection (n=145), uncomplicated dengue (n=67), and severe dengue (n=36) in Morelos. 24911936

2014

dbSNP: rs4804803
rs4804803
0.070 GeneticVariation BEFREE Polymorphisms in the promoter region of CD209 gene (rs735239, rs4804803, rs2287886) were investigated in 112 hospitalized cases of dengue (DEN) and 104 healthy controls to find out whether they are associated with dengue in a Western Indian population. 23624202

2013

dbSNP: rs4804803
rs4804803
0.070 GeneticVariation BEFREE Previously the severity and outcome of dengue fever and hepatitis C (diseases caused by viruses from the family Flaviviridae) were associated with the rs4804803 single nucleotide polymorphism (SNP) located in the promoter region of the human CD209 gene. 22061615

2012

dbSNP: rs4804803
rs4804803
0.070 GeneticVariation BEFREE the rs4804803 SNP in the CD209 promoter contributed to susceptibility to dengue infection and complication of DHF. 21245921

2011

dbSNP: rs4804803
rs4804803
0.070 GeneticVariation BEFREE A single nucleotide polymorphism (SNP) in the promoter region of CD209 (-336 A/G; rs4804803) affects transcription and is associated with the severity of tuberculosis and dengue fever. 20470843

2010

dbSNP: rs1732778
rs1732778
0.020 GeneticVariation BEFREE Polymorphisms in the OAS1 SNPs (rs1131454), OAS2 SNPs (rs1293762, rs15895 and rs1732778) and OAS3 SNPs (rs2285932 and rs2072136) genes were studied using PCR followed by restriction fragment length polymorphism methods in 30 patients for dengue infection and 40 control group who have no documented evidence of symptomatic dengue. 24819159

2015

dbSNP: rs1799964
rs1799964
0.020 GeneticVariation BEFREE Under recessive genetic model (C/C vs. T/T+T/C), the TNF rs1799964 C/C genotype was significantly associated with DEN [P=0.014, OR with 95% CI 3.07 (1.18-7.98)]. 25890879

2015

dbSNP: rs1801274
rs1801274
0.020 GeneticVariation BEFREE A single-nucleotide polymorphism in FcγRIIa (rs1801274) results in altered affinity of the receptor for different subclasses of immunoglobulin G, and is a key player in determining the susceptibility to or protection from severe clinical infection of dengue. 26240159

2015

dbSNP: rs2072136
rs2072136
0.020 GeneticVariation BEFREE Polymorphisms in the OAS1 SNPs (rs1131454), OAS2 SNPs (rs1293762, rs15895 and rs1732778) and OAS3 SNPs (rs2285932 and rs2072136) genes were studied using PCR followed by restriction fragment length polymorphism methods in 30 patients for dengue infection and 40 control group who have no documented evidence of symptomatic dengue. 24819159

2015

dbSNP: rs1801274
rs1801274
0.020 GeneticVariation BEFREE In this study, real-time PCR was used to characterize the distribution of rs1801274 and rs4804803 in subjects with asymptomatic dengue infection (n=145), uncomplicated dengue (n=67), and severe dengue (n=36) in Morelos. 24911936

2014

dbSNP: rs3132468
rs3132468
0.020 GeneticVariation BEFREE The reported DSS-risk alleles were significantly associated with DSS in Thai patients with dengue (one-sided P = 0.0213 and odds ratio [OR] = 1.58 for rs3132468-C and one-sided P = 0.0252 and OR = 1.49 for rs3765524-C). 24884822

2014

dbSNP: rs1732778
rs1732778
0.020 GeneticVariation BEFREE Polymorphisms in the OAS1 (rs1131454 and rs10774671), OAS3 (rs2285932 and rs2072136) and OAS2 (rs15895 and rs1732778) genes were studied using PCR followed by restriction fragment length polymorphism methods in 109 patients hospitalized for dengue (DEN) and 105 healthy controls (HCs) who have no documented evidence of symptomatic dengue. 23337612

2013

dbSNP: rs1799964
rs1799964
0.020 GeneticVariation BEFREE The frequency of rs1799964 'C/C' genotype of the TNF gene was found to be significantly higher in all patient groups compared to HCs [HCs vs. DEN, P=0.0054, Pc=0.0162, OR 3.57; HCs vs. DF, P=0.036, OR 2.89; HCs vs. DHF, P=0.0088, Pc=0.0240, OR 5.11]. 23380141

2013

dbSNP: rs2072136
rs2072136
0.020 GeneticVariation BEFREE Polymorphisms in the OAS1 (rs1131454 and rs10774671), OAS3 (rs2285932 and rs2072136) and OAS2 (rs15895 and rs1732778) genes were studied using PCR followed by restriction fragment length polymorphism methods in 109 patients hospitalized for dengue (DEN) and 105 healthy controls (HCs) who have no documented evidence of symptomatic dengue. 23337612

2013

dbSNP: rs3132468
rs3132468
0.020 GeneticVariation BEFREE This study confirms that the MICB rs3132468 and PLCE1 rs3740360 risk genotypes are not only associated with DSS, but are also associated with less severe clinical phenotypes of dengue, as well as with dengue in infants. 23536857

2013

dbSNP: rs12252
rs12252
0.010 GeneticVariation BEFREE In naturally occurring, genetic loss-of-function studies, MKs from healthy subjects harboring a homozygous mutation in IFITM3 (rs12252-C, a common single-nucleotide polymorphism in areas of the world where DENV is endemic) were significantly more susceptible to DENV infection. 30723081

2019

dbSNP: rs1799983
rs1799983
0.010 GeneticVariation BEFREE For the ENOS (rs1799983) SNP, the genotype GT was positively associated with protection for development of the clinical form in DHF compared to dengue fever (OR = 0.39, 95% CI = (0.13-1.14), p = 0.0058) in codominant GG/GT/TT and overdominant model GT vs GG + TT (OR = 0.35, 95% CI = (0.12-1.02), p = 0.04). 30452889

2019

dbSNP: rs1805016
rs1805016
0.010 GeneticVariation BEFREE We found IL4R-rs1805016 GG genotype and G-allele carriers and IL6R-rs8192284 AA genotype associated with clinical dengue in the pooled and Huila samples. 30228077

2019

dbSNP: rs3739319
rs3739319
0.010 GeneticVariation BEFREE We genotyped 193 of the dengue cases using quantitative polymerase chain reaction to the SNP rs3739319. 31194647

2019

dbSNP: rs8192284
rs8192284
0.010 GeneticVariation BEFREE We found IL4R-rs1805016 GG genotype and G-allele carriers and IL6R-rs8192284 AA genotype associated with clinical dengue in the pooled and Huila samples. 30228077

2019

dbSNP: rs1285933
rs1285933
0.010 GeneticVariation BEFREE Association of rs1285933 single nucleotide polymorphism in CLEC5A gene with dengue severity and its functional effects. 28764923

2017

dbSNP: rs385893
rs385893
0.010 GeneticVariation BEFREE To examine the possible association of these SNPs with DHF, 918 Thai patients with dengue [509 patients with DHF and 409 with dengue fever (DF)] were genotyped for five SNPs: rs5745568 in BAK1, rs6141 in THPO, rs6065 in GP1BA, rs739496 in SH2B3, and rs385893 in RCL1. 27401010

2016

dbSNP: rs5745568
rs5745568
0.010 GeneticVariation BEFREE To examine the possible association of these SNPs with DHF, 918 Thai patients with dengue [509 patients with DHF and 409 with dengue fever (DF)] were genotyped for five SNPs: rs5745568 in BAK1, rs6141 in THPO, rs6065 in GP1BA, rs739496 in SH2B3, and rs385893 in RCL1. 27401010

2016