|
rs498005
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Results:</b> C allele of rs498005 was significantly correlated with increased risk of AF (OR = 1.412, 95%CI = 1.012-1.970), and the association still exited after adjustment by age, gender, the status of smoking and drinking, histories of diabetes, hyperlipidaemia and myocardial infarction (adjusted OR = 1.473, 95%CI = 1.043-2.081).
|
31315459 |
2019 |
|
rs5215
|
|
|
0.020 |
GeneticVariation |
BEFREE |
48% and 47% had 1 or 2 diabetes risk alleles of rs5215 and rs5219, respectively.
|
30169531 |
2018 |
|
rs12255372
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Diabetes disease stage was marginally significantly associated with the frequency of the T variant at rs12255372 (p=0.057; adjusted p=0.017) but not at rs7903146 (p=0.5; adjusted p=0.2).
|
18282631 |
2008 |
|
rs7903146
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Diabetes disease stage was marginally significantly associated with the frequency of the T variant at rs12255372 (p=0.057; adjusted p=0.017) but not at rs7903146 (p=0.5; adjusted p=0.2).
|
18282631 |
2008 |
|
rs7903146
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Diabetes-associated variation (T allele at rs7903146) in TCF7L2 may impair the ability of hyperglycemia to suppress glucagon (45 ± 2 vs. 47 ± 2 vs. 60 ± 5 ng/L for CC, CT, and TT, respectively, P = 0.02).
|
22461567 |
2012 |
|
rs1801282
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Diabetes risk alleles in PPAR-γ2 (rs1801282) and PTPRD (rs17584499) are associated with pioglitazone therapeutic efficacy.
|
23147557 |
2013 |
|
rs17584499
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Diabetes risk alleles in PPAR-γ2 (rs1801282) and PTPRD (rs17584499) are associated with pioglitazone therapeutic efficacy.
|
23147557 |
2013 |
|
rs1036483919
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The heterozygous T130I mutation was the unique functional gene variation that could explain diabetes phenotype.
|
25361053 |
2014 |
|
rs952497863
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The heterozygous T130I mutation was the unique functional gene variation that could explain diabetes phenotype.
|
25361053 |
2014 |
|
rs2228570
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Diabetes duration, SBP, HbA1c, and the rs2228570 T allele were associated with increased risk of DR. VDR rs2228570 might be good candidate biomarker of DR in Han Chinese T2DM patients.
|
25899017 |
2015 |
|
rs2605039
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results suggest that the contribution of diabetes to breast cancer risk might be modified by IL-6 rs1800796 and HSPD1 rs2605039.
|
28591216 |
2017 |
|
rs4876369
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Diabetes status modified the associations between rs4876369 and rs2241745 and BC incidence, on the multiplicative interaction scale.
|
30457165 |
2019 |
|
rs2241745
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Diabetes status modified the associations between rs4876369 and rs2241745 and BC incidence, on the multiplicative interaction scale.
|
30457165 |
2019 |
|
rs9939609
|
|
|
0.800 |
GeneticVariation |
BEFREE |
Diabetes genomics research has illuminated single nucleotide polymorphism (SNP) in several genes including, fat mass and obesity associated (FTO) (rs9939609 and rs9926289), potassium voltage-gated channel subfamily J member 11 (rs5219), SLC30A 8 (rs13266634) and peroxisome proliferator-activated receptor gamma 2 (rs1805192).
|
31823921 |
2019 |
|
rs9926289
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Diabetes genomics research has illuminated single nucleotide polymorphism (SNP) in several genes including, fat mass and obesity associated (FTO) (rs9939609 and rs9926289), potassium voltage-gated channel subfamily J member 11 (rs5219), SLC30A 8 (rs13266634) and peroxisome proliferator-activated receptor gamma 2 (rs1805192).
|
31823921 |
2019 |
|
rs5219
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Diabetes genomics research has illuminated single nucleotide polymorphism (SNP) in several genes including, fat mass and obesity associated (FTO) (rs9939609 and rs9926289), potassium voltage-gated channel subfamily J member 11 (rs5219), SLC30A 8 (rs13266634) and peroxisome proliferator-activated receptor gamma 2 (rs1805192).
|
31823921 |
2019 |
|
rs13266634
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Diabetes genomics research has illuminated single nucleotide polymorphism (SNP) in several genes including, fat mass and obesity associated (FTO) (rs9939609 and rs9926289), potassium voltage-gated channel subfamily J member 11 (rs5219), SLC30A 8 (rs13266634) and peroxisome proliferator-activated receptor gamma 2 (rs1805192).
|
31823921 |
2019 |
|
rs1805192
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Diabetes genomics research has illuminated single nucleotide polymorphism (SNP) in several genes including, fat mass and obesity associated (FTO) (rs9939609 and rs9926289), potassium voltage-gated channel subfamily J member 11 (rs5219), SLC30A 8 (rs13266634) and peroxisome proliferator-activated receptor gamma 2 (rs1805192).
|
31823921 |
2019 |
|
rs1042714
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Gln27Glu variant of the beta2-adrenergic receptor gene is not associated with obesity and diabetes in Japanese-Americans.
|
11288039 |
2001 |
|
rs150179526
|
|
|
0.010 |
GeneticVariation |
BEFREE |
V125I mutation co-segregated in those 2 initial families, but further association studies showed that this mutation was not associated with diabetes or early age at diagnosis of the disease.
|
11773861 |
2002 |
|
rs1805002
|
|
|
0.010 |
GeneticVariation |
BEFREE |
V125I mutation co-segregated in those 2 initial families, but further association studies showed that this mutation was not associated with diabetes or early age at diagnosis of the disease.
|
11773861 |
2002 |
|
rs1801262
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Ala45Thr polymorphism of the NEUROD1 gene and diabetes susceptibility: a meta-analysis.
|
15592940 |
2005 |
|
rs121917718
|
|
|
0.010 |
GeneticVariation |
BEFREE |
R164W segregated with diabetes in the family of the proband and in vitro studies showed that it impairs the repressor activity of PAX4 on the insulin and glucagon promoters.
|
17426099 |
2007 |
|
rs2281939
|
|
|
0.030 |
GeneticVariation |
BEFREE |
T228A polymorphism of SORBS1 was not associated with the prevalence of diabetes.
|
18394047 |
2008 |
|
rs1320702652
|
|
|
0.010 |
GeneticVariation |
BEFREE |
C34T AMPD1 polymorphism may be associated with reduced frequency of obesity in CAD patients and of hyperglycaemia and diabetes in both CAD and HF patients.
|
18855224 |
2009 |