|
rs10484821
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The genome-wide association study identified 26 SNPs associated with new-onset diabetes after transplantation; this association was validated for eight SNPs (rs10484821, rs7533125, rs2861484, rs11580170, rs2020902, rs1836882, rs198372, and rs4394754) by de novo genotyping.
|
24309190 |
2014 |
|
rs10486567
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The JAZF1 SNPs rs6968704 and rs10486567 were associated with decreased risk of prostate cancer but were not associated with diabetes.
|
19998368 |
2010 |
|
rs10489177
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs10489177 GG genotype was associated with significantly increased risk for IS in individuals without hypertension (OR = 2.78, 95 % CI = 1.59-4.86) and in individuals without diabetes (OR = 1.93, 95 % CI = 1.27-2.94).
|
24122314 |
2014 |
|
rs104894014
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The second activating glucokinase mutation (A456V): implications for glucose homeostasis and diabetes therapy.
|
11916951 |
2002 |
|
rs1049353
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A total of 1,064 obese subjects (BMI > or = 30 kg/m2) without diabetes, impaired glucose tolerance or other endocrine diseases and 251 healthy control persons were genotyped for the G1422A variant (rs1049353) with a TaqMan assay.
|
17873324 |
2007 |
|
rs10494366
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We have independently replicated the association between rs10494366 in NOS1AP and incident diabetes among white CCB users.
|
19943157 |
2010 |
|
rs10497721
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association with diabetes-related traits in the Framingham Heart Study.
|
17903298 |
2007 |
|
rs1050450
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This is the first paper to examine the rs1050450 variant in two samples of Caucasian subjects with diabetes.
|
21185702 |
2012 |
|
rs1050828
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A recently published example is the erythrocytic variant (rs1050828) in G6PD, which leads to the artificial lowering of HbA1c and missed diagnosis of diabetes using current thresholds.
|
29522974 |
2018 |
|
rs10509291
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Among metabolically characterized subjects with normal glucose tolerance (N=243), those carrying the diabetes risk allele (T) for rs10509291 and (G) for rs7896005 had a reduced acute insulin response (AIR) to an intravenous glucose bolus (adjusted P=0.045 and 0.035, respectively).
|
21871827 |
2011 |
|
rs10517086
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three single nucleotide polymorphisms were associated with increased diabetes risk (rs10517086_A [<i>P</i> = 0.03], rs1534422_G [<i>P</i> = 0.006], and rs2327832_G [<i>P</i> = 0.03] in <i>TNFAIP3</i>) and one with decreased risk (rs1004446_A in <i>INS</i> [<i>P</i> = 0.006]).
|
28903990 |
2017 |
|
rs1052700
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The PLIN polymorphisms significantly interacted with central obesity in relation to diabetes risk (P for interaction = 0.036, 0.033, and 0.042 for rs1052700, rs894160, and rs2304796, respectively).
|
23517113 |
2013 |
|
rs1056534
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, this is the first study describing significant relationship of FN3K (rs1056534) and (rs3848403) polymorphisms with concentration of sRAGE in patients with diabetes.
|
24908234 |
2014 |
|
rs1057293
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In additive models adjusted for hypertension, smoking and diabetes, the major allele (G) of rs1057293 was associated (odds ratio, 95% confidence interval; P value) with ischaemic stroke with similar effect size in both studies; in Lund (1.35, 1.11-1.64; P=0.002) and Malmö (1.30, 1.03-1.65; P=0.027).
|
21430556 |
2011 |
|
rs1057520504
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We also observed cosegregation with diabetes of the Arg263His coding region mutation in eight members of one MODY family, whereas it was absent in nondiabetic subjects of this family.
|
19336507 |
2009 |
|
rs1060366
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Thus, allele A of G94A SNP (rs1060366) could be a risk allele for diabetes susceptibility among Egyptian patients.
|
31523248 |
2019 |
|
rs1061170
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Contribution of complement factor H Y402H polymorphism to sudden sensorineural hearing loss risk and possible interaction with diabetes.
|
22426290 |
2012 |
|
rs1061170
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The common Y402H variant in the CFH gene was not associated with classical cardiovascular risk factors (diabetes, hypercholesterolaemia, hypertension, obesity, smoking and C-reactive protein serum levels).
|
17472578 |
2007 |
|
rs10636
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Using the PCR-based restriction fragment length polymorphism method, seven single nucleotide polymorphisms (SNPs) in MT genes (rs8052394 and rs11076161 in MT1A gene, rs8052334, rs964372, and rs7191779 in MT1B gene, rs708274 in MT1E gene, and rs10636 in MT2A gene) were detected in 851 Chinese people of Han descent (397 diabetes and 454 controls).
|
18349110 |
2008 |
|
rs1063856
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three known vWF gene polymorphisms were genotyped in a group of 493 type I diabetic subjects, all showing proliferative retinopathy, but with various stages of renal involvement, which ranged from no microalbuminuria, despite a mean duration of diabetes of 31 years, to advanced nephropathy (GENEDIAB Study): Thr789Ala (Rsa I), M-/M+ (Msp I) (intron 19), and Ala1381Thr (Hph I).
|
10760079 |
2000 |
|
rs1073203
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two SNPs (rs1073203 and rs4838605) were found to be significantly associated with DR in patients with diabetes after adjusting for covariants; rs1073203-G (P = 0.012, odds ratio [OR] = 0.317, 95% confidence interval [95% CI]: 0.129-0.778), rs1073203 in a dominant model (P = 0.005, OR = 0.251, 95% CI: 0.096-0.655), rs4838605 in an additive model (P = 0.047, OR = 1.650, 95% CI: 1.007-2.703), In a dominant model rs1073203 (P = 0.027, OR = 1.400, 95% CI: 0.101-0.857), was significantly associated with DR in type 2 diabetes after adjustment for covariants.
|
24526447 |
2014 |
|
rs10741657
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the general population, genetic variants affecting vitamin D metabolism (<i>DHCR7</i> rs12785878, <i>CYP2R1</i> rs10741657, <i>GC</i> rs4588) have been associated with serum vitamin D. We studied the association of these variants with serum vitamin D in 2163 patients with T2D from the "Sapienza University Mortality and Morbidity Event Rate (SUMMER) study in diabetes".
|
30405883 |
2018 |
|
rs10747983
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Associations between 4 AVPR1A tag single nucleotide polymorphisms (rs1042615, rs10784339, rs7308855, and rs10747983) and diabetes status, glucose and triglyceride concentrations, and BMI were analyzed.
|
19056558 |
2009 |
|
rs10757272
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Subjects with rs10757272 were found to have an increased odds ratio (OR) of having severe CAC in multivariate logistic regression analysis after adjusting for age, sex, hypertension, and diabetes (adjusted OR 3.24 and 95% CI 2.11-4.97).
|
30921371 |
2019 |
|
rs10757274
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The frequency of diabetes was lower in patients carrying GG genotype for rs10757274, rs2383206 and rs10757278 (29.4%, 32.8%, 32.0%) compared to patients carrying AA or AG genotypes (49.1% and 39.2%, p = 0.01; 52.4% and 40.1%, p = 0.01; 47.8% and 37.9%, p = 0.04; respectively).
|
22856518 |
2012 |