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rs28938469
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We explored the gene responsible for diabetes in two brothers, who were suspected to have diabetes </span>at 15 and 18 years-of-age, respectively, with whole exome sequencing, and identified a compound heterozygous ABCC8 gene mutation (p.Arg168Cys and p.Arg1421Cys).
|
31479591 |
2020 |
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rs36217263
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|
|
0.010 |
GeneticVariation |
BEFREE |
The deletion of at least one copy of allele A of rs36217263 near Klotho showed statistically significant association with poor response to beta-blockers (dominant; odds ratio (OR) = 3.89; P = 0.017), adjusted for diabetes and dyslipidemia.
|
31350855 |
2020 |
|
rs505151
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In CAD patients, the AG genotype of PSCK9 rs505151 is associated with diabetes and a positive family history of CAD.
|
30947598 |
2020 |
|
rs756823374
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We explored the gene responsible for diabetes in two brothers, who were suspected to have diabetes at 15 and 18 years-of-age, respectively, with whole exome sequencing, and identified a compound heterozygous ABCC8 gene mutation (p.Arg168Cys and p.Arg1421Cys).
|
31479591 |
2020 |
|
rs8133052
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Regarding the docetaxel phase, high levels of abdominal pain and mucositis were related to CBR3 gene (rs8133052) polymorphism and diabetes respectively.
|
31056713 |
2020 |
|
rs1057520291
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Herein, we present a child who was diagnosed with CHI at birth, then developed diabetes mellitus at the age of nine years due to a novel homozygous missense, p.L171F (c.511C>T) mutation in exon 4 of <i>ABCC8</i>.
|
29739729 |
2019 |
|
rs1060366
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Thus, allele A of G94A SNP (rs1060366) could be a risk allele for diabetes susceptibility among Egyptian patients.
|
31523248 |
2019 |
|
rs10757272
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Subjects with rs10757272 were found to have an increased odds ratio (OR) of having severe CAC in multivariate logistic regression analysis after adjusting for age, sex, hypertension, and diabetes (adjusted OR 3.24 and 95% CI 2.11-4.97).
|
30921371 |
2019 |
|
rs11136000
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs11136000 genotypes in combination with HDL levels and knowledge about diabetes background may be used as a predictive medicine tool for cognitive disorders.
|
30560405 |
2019 |
|
rs11207997
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Cox proportional hazard models showed that the </span>rs1120</span>7997 T allele is associated with a lower risk of D</span>M after adjusting for covariates (hazard ratio: 0.90, 95% confidence interval: 0.812-0.998, p = 0.046).
|
30683883 |
2019 |
|
rs12513649
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CREBRF rs12513649 and rs373863828 were genotyped in 2022 participants in a community-based cross-sectional study designed to identify determinants of diabetes and end-stage renal disease (ESRD).
|
31280340 |
2019 |
|
rs184003
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs184003 SNP seems related to coronary artery disease, breast cancer, and diabetes.
|
30863465 |
2019 |
|
rs192902098
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In this study, we screened a large cohort of subjects with increased risk for diabetes and identified two subjects with impaired glucose tolerance carrying common, heterozygous, missense mutations in the PDX1 coding region leading to single amino acid exchanges (P33T, C18R) in its transactivation domain.
|
30930126 |
2019 |
|
rs200879349
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here we describe a loss-of-function <i>SLC19A2</i> mutation (c.A1063C: p.Lys355Gln) in a family with early-onset diabetes and mild TRMA traits transmitted in an autosomal dominant fashion.
|
30833467 |
2019 |
|
rs2066853
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In acromegaly, GSTP1 gene methylation associates with resistance to SSA treatment, especially in patients carrying also the AHR rs2066853 variant, and with increased prevalence of colonic polyps and diabetes mellitus.
|
30488289 |
2019 |
|
rs2241745
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Diabetes status modified the associations between rs4876369 and rs2241745 and BC incidence, on the multiplicative interaction scale.
|
30457165 |
2019 |
|
rs2278426
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association between rs2278426 (C/T) and rs892066 (C/G) variants of ANGPTL8 (betatrophin) and susceptibility to type2 diabetes mellitus.
|
30191588 |
2019 |
|
rs370963321
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We discovered three HDAC4 mutations (p.His227Arg, p.Asp234Asn, and p.Glu374Lys) in unrelated individuals who had nonautoimmune diabetes with various degrees of β-cell loss.
|
30968599 |
2019 |
|
rs372098146
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here we expressed, in dPdxk<sup>1</sup> mutant flies, four PDXK human variants: three (D87H, V128I and H246Q) listed in databases, and one (A243G) found in a genetic screening in patients with diabetes.
|
31578392 |
2019 |
|
rs3733197
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study was the first to demonstrate that a BANK1 gene SNP (rs3733197) could confer genetic predisposition in PM/DM patients and PM/DM patients with ILD in a Chinese Han population.
|
30145638 |
2019 |
|
rs373863828
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Meta-analyses combining the current results with previous results in Polynesians showed a strong association between the A allele at rs373863828 and BMI (β = 1.38 kg/m<sup>2</sup>; p = 2.5 × 10<sup>-29</sup>) and diabetes (OR 0.65, p = 1.5 × 10<sup>-13</sup>).
|
31280340 |
2019 |
|
rs3745297
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The patient age was younger and rate of diabetes and hypertension lower in the PAF patients with Ser96Ala than in those without (TT/TG/GG, 179/120/35; 64±10/60±12/59±13 y, P = 0.001; 18.5/ 9.2/8.6%, P = 0.04 and 66.1/50.0/37.1%, P = 0.001, respectively).
|
30840693 |
2019 |
|
rs377592729
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here we expressed, in dPdxk<sup>1</sup> mutant flies, four PDXK human variants: three (D87H, V128I and H246Q) listed in databases, and one (A243G) found in a genetic screening in patients with diabetes.
|
31578392 |
2019 |
|
rs4376531
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our data suggested that GC and GG/GC of rs4376531 contributed to a decreased risk of AS while CC genotype, interacting with diabetes, increased the stroke risk in Han Chinese population.
|
30149742 |
2019 |
|
rs4717806
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Finally, a statistical association of rs4717806(AA) genotype with higher TyG index in IHD patients (P = .03) was highlighted by multiple regression analysis considering log-transformed biochemical parameters as dependent variable and presence of coronary artery disease, age, gender, waist circumference, presence of diabetes as predictors.
|
31192914 |
2019 |