Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs587783672
rs587783672
T 0.720 CausalMutation CLINVAR

dbSNP: rs193929355
rs193929355
T 0.710 CausalMutation CLINVAR

dbSNP: rs80356625
rs80356625
A 0.710 CausalMutation CLINVAR

dbSNP: rs1057515576
rs1057515576
GAAAA 0.700 CausalMutation CLINVAR

dbSNP: rs1057518903
rs1057518903
A 0.700 CausalMutation CLINVAR

dbSNP: rs1135401784
rs1135401784
CP
G 0.700 GeneticVariation CLINVAR

dbSNP: rs1553769428
rs1553769428
HJV
A 0.700 CausalMutation CLINVAR

dbSNP: rs1559279177
rs1559279177
HJV
T 0.700 CausalMutation CLINVAR

dbSNP: rs28936415
rs28936415
A 0.700 GeneticVariation CLINVAR

dbSNP: rs386134141
rs386134141
CP
A 0.700 GeneticVariation CLINVAR

dbSNP: rs587783669
rs587783669
C 0.700 GeneticVariation CLINVAR

dbSNP: rs587783673
rs587783673
T 0.700 CausalMutation CLINVAR

dbSNP: rs587783675
rs587783675
G 0.700 CausalMutation CLINVAR

dbSNP: rs886040857
rs886040857
A 0.700 CausalMutation CLINVAR

dbSNP: rs498005
rs498005
0.010 GeneticVariation BEFREE <b>Results:</b> C allele of rs498005 was significantly correlated with increased risk of AF (OR = 1.412, 95%CI = 1.012-1.970), and the association still exited after adjustment by age, gender, the status of smoking and drinking, histories of diabetes, hyperlipidaemia and myocardial infarction (adjusted OR = 1.473, 95%CI = 1.043-2.081). 31315459

2019

dbSNP: rs5215
rs5215
0.020 GeneticVariation BEFREE 48% and 47% had 1 or 2 diabetes risk alleles of rs5215 and rs5219, respectively. 30169531

2018

dbSNP: rs12255372
rs12255372
0.090 GeneticVariation BEFREE Diabetes disease stage was marginally significantly associated with the frequency of the T variant at rs12255372 (p=0.057; adjusted p=0.017) but not at rs7903146 (p=0.5; adjusted p=0.2). 18282631

2008

dbSNP: rs7903146
rs7903146
0.100 GeneticVariation BEFREE Diabetes disease stage was marginally significantly associated with the frequency of the T variant at rs12255372 (p=0.057; adjusted p=0.017) but not at rs7903146 (p=0.5; adjusted p=0.2). 18282631

2008

dbSNP: rs7903146
rs7903146
0.100 GeneticVariation BEFREE Diabetes-associated variation (T allele at rs7903146) in TCF7L2 may impair the ability of hyperglycemia to suppress glucagon (45 ± 2 vs. 47 ± 2 vs. 60 ± 5 ng/L for CC, CT, and TT, respectively, P = 0.02). 22461567

2012

dbSNP: rs1801282
rs1801282
0.100 GeneticVariation BEFREE Diabetes risk alleles in PPAR-γ2 (rs1801282) and PTPRD (rs17584499) are associated with pioglitazone therapeutic efficacy. 23147557

2013

dbSNP: rs17584499
rs17584499
0.020 GeneticVariation BEFREE Diabetes risk alleles in PPAR-γ2 (rs1801282) and PTPRD (rs17584499) are associated with pioglitazone therapeutic efficacy. 23147557

2013

dbSNP: rs1799983
rs1799983
0.100 GeneticVariation BEFREE Diabetes mellitus and late-onset hypogonadism: the role of Glu298Asp endothelial nitric oxide synthase polymorphism. 25228279

2015

dbSNP: rs1036483919
rs1036483919
GCK
0.020 GeneticVariation BEFREE The heterozygous T130I mutation was the unique functional gene variation that could explain diabetes phenotype. 25361053

2014

dbSNP: rs952497863
rs952497863
0.020 GeneticVariation BEFREE The heterozygous T130I mutation was the unique functional gene variation that could explain diabetes phenotype. 25361053

2014

dbSNP: rs2228570
rs2228570
VDR
0.010 GeneticVariation BEFREE Diabetes duration, SBP, HbA1c, and the rs2228570 T allele were associated with increased risk of DR. VDR rs2228570 might be good candidate biomarker of DR in Han Chinese T2DM patients. 25899017

2015