Variant Gene Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1060499866
rs1060499866
0.010 GeneticVariation BEFREE The HNF1A mutant Ala180Val: Clinical challenges in determining causality of a rare HNF1A variant in familial diabetes. 28934671

2018

dbSNP: rs10767664
rs10767664
0.010 GeneticVariation BEFREE This study is aimed at analyzing the effects of rs10767664 BDNF gene polymorphism on diabetes mellitus prevalence, body weight, cardiovascular risk factors, and serum adipokine levels in obese female patients. 28595187

2018

dbSNP: rs749317102
rs749317102
0.010 GeneticVariation BEFREE In vivo measurement and biological characterisation of the diabetes-associated mutant insulin p.R46Q (GlnB22-insulin). 28478482

2018

dbSNP: rs187238
rs187238
0.010 GeneticVariation BEFREE The aim of this study was to evaluate association between G(-137)C polymorphism (rs187238) in the IL-18 gene and risk of diabetes and CVD in type 2 diabetes patients. 27741477

2017

dbSNP: rs231356
rs231356
0.010 GeneticVariation BEFREE Increased DNA methylation at cg23161492 was associated with decreased gene expression levels of ANPEP (p = 8.9 × 10(-5)). rs231356-T, which was associated with hypomethylation of cg26963277 (KCNQ1), was associated with a higher odds of diabetes (OR 1.06, p = 1.3 × 10(-5)). 26825526

2017

dbSNP: rs237025
rs237025
0.010 GeneticVariation BEFREE Association of donor and recipient SUMO4 rs237025 genetic variant with new-onset diabetes mellitus after liver transplantation in a Chinese population. 28689037

2017

dbSNP: rs4374383
rs4374383
0.010 GeneticVariation BEFREE MERTK rs4374383 variant predicts incident nonalcoholic fatty liver disease and diabetes: role of mononuclear cell activation and adipokine response to dietary fat. 28334911

2017

dbSNP: rs1024611
rs1024611
0.010 GeneticVariation BEFREE Multivariate Cox regression analysis, taking into the account the recipient's sex, age and BMI, as well as the number of G alleles of the CCL2 rs1024611 polymorphism, revealed that this polymorphism is an independent risk factor for post-transplant diabetes. 26802601

2016

dbSNP: rs10719
rs10719
0.010 GeneticVariation BEFREE Furthermore, patients diagnosed with hypertension or DM who carried the DROSHA rs10719 CC genotype showed increased CRC risk, while the XPO5 rs11077 AC+CC genotype led to increased CRC risk in patients with hypertension only. 26147304

2016

dbSNP: rs12522383
rs12522383
0.010 GeneticVariation BEFREE However, SNP rs12522383 in WDR36 was associated with diabetes mellitus (p = 0.00008). 25669751

2016

dbSNP: rs14035
rs14035
RAN
0.010 GeneticVariation BEFREE Stratified analysis revealed the RAN rs14035 combined CT+TT genotype was associated with decreased CRC risk in male patients without diabetes mellitus (DM) and in patients with rectal cancer. 26147304

2016

dbSNP: rs1543654
rs1543654
0.010 GeneticVariation BEFREE In joint analysis of 90,003 IBC and Cardiometabochip SNPs, rs1543654 in the region of KCNE1 predicted change in BDI scores at Year 1 in diabetes support and education (β = -1.05, standard error [SE] = 0.21, p = 6.9 × 10(-7)) at the level of chip-wide significance, while also showing a nominal association with baseline BDI (β = 0.35, SE = 0.16, p = .026). 26489030

2016

dbSNP: rs1551305
rs1551305
0.010 GeneticVariation BEFREE The AA genotype of rs1551305 was associated with a higher diabetes risk (p<0.05). 26918892

2016

dbSNP: rs1800629
rs1800629
TNF
0.010 GeneticVariation BEFREE An association between the A allele of rs1800629 and type of diabetes was found. 26821796

2016

dbSNP: rs181914932
rs181914932
0.010 GeneticVariation BEFREE Triglyceride levels (P = 0.0042), diabetes (P = 7.28 × 10(-5)), paraoxonase 1 (PON1) activity (P = 0.019), statin use (P = 0.026), PLTP SNP rs4810479 (P = 6.38 × 10(-7)), and PCIF1 SNP rs181914932 (P = 0.041) were all significantly associated with PLTPa. 26009633

2016

dbSNP: rs2188380
rs2188380
0.010 GeneticVariation BEFREE Five gout susceptibility loci were identified at the genome-wide significance level (p<5.0×10(-8)), which contained well-known urate transporter genes (ABCG2 and SLC2A9) and additional genes: rs1260326 (p=1.9×10(-12); OR=1.36) of GCKR (a gene for glucose and lipid metabolism), rs2188380 (p=1.6×10(-23); OR=1.75) of MYL2-CUX2 (genes associated with cholesterol and diabetes mellitus) and rs4073582 (p=6.4×10(-9); OR=1.66) of CNIH-2 (a gene for regulation of glutamate signalling). 25646370

2016

dbSNP: rs2276415
rs2276415
0.010 GeneticVariation BEFREE A χ(2)-test and multivariable logistic regression analysis with adjustments for age, sex, baseline serum creatinine, and underlying comorbid disease covariates showed a significant association between rs2276415 and the prevalence of any event of acute kidney injury and chronic kidney disease (CKD) in diabetic patients but not in patients without diabetes. 26719361

2016

dbSNP: rs2284912
rs2284912
0.010 GeneticVariation BEFREE In the longitudinal study, we found individuals carrying TA/AA genotypes of rs6044695 or TC/CC genotypes of rs2284912 had lower incidence of diabetes during the 5-year follow-up. 26607656

2016

dbSNP: rs2327832
rs2327832
0.010 GeneticVariation BEFREE Moreover, we identify the single nucleotide polymorphism rs2327832 of TNFAIP3 as a possible prognostic marker for diabetes outcome in children with T1D. 26652732

2016

dbSNP: rs3184504
rs3184504
0.010 GeneticVariation BEFREE However, there was no significant association between R262W and fasting glucose, HbA1c or incidence of diabetes. 26891449

2016

dbSNP: rs35439639
rs35439639
0.010 GeneticVariation BEFREE Four tag single nucleotide polymorphisms (SNPs: rs35810727, rs28373064, rs35439639, rs35608965) of AVPR1B were genotyped in the cardiovascular cohort (n=6103) of MDC (MDC-CC) and associated with measures of obesity and DM. 26503846

2016

dbSNP: rs35608965
rs35608965
0.010 GeneticVariation BEFREE Four tag single nucleotide polymorphisms (SNPs: rs35810727, rs28373064, rs35439639, rs35608965) of AVPR1B were genotyped in the cardiovascular cohort (n=6103) of MDC (MDC-CC) and associated with measures of obesity and DM. 26503846

2016

dbSNP: rs35810727
rs35810727
0.010 GeneticVariation BEFREE In MDC-CC there was no association between the major allele of rs35810727 and DM, but in the complete MDC cohort (n=30 447) the major allele of rs35810727 was associated with DM (OR (95% CI); 1.10 (1.00-1.20), P=0.04). 26503846

2016

dbSNP: rs4073582
rs4073582
0.010 GeneticVariation BEFREE Five gout susceptibility loci were identified at the genome-wide significance level (p<5.0×10(-8)), which contained well-known urate transporter genes (ABCG2 and SLC2A9) and additional genes: rs1260326 (p=1.9×10(-12); OR=1.36) of GCKR (a gene for glucose and lipid metabolism), rs2188380 (p=1.6×10(-23); OR=1.75) of MYL2-CUX2 (genes associated with cholesterol and diabetes mellitus) and rs4073582 (p=6.4×10(-9); OR=1.66) of CNIH-2 (a gene for regulation of glutamate signalling). 25646370

2016

dbSNP: rs4607517
rs4607517
0.010 GeneticVariation BEFREE A genetic variant near the glucokinase gene (rs4607517) was significantly associated with progression to prediabetes or diabetes (hazard ratio 1·27, 1·16-1·38; p=1·70 × 10(-7)). 26577716

2016