Variant Gene Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10010131
rs10010131
0.010 GeneticVariation BEFREE We genotyped the WFS1 SNPs rs10010131, rs752854 and rs734312 (H611R) in 3,548 DPP participants and performed Cox regression analysis using genotype, intervention and their interactions as predictors of diabetes incidence. 18060660

2008

dbSNP: rs10012946
rs10012946
0.010 GeneticVariation BEFREE Examination of the publicly available Diabetes Genetics Initiative genome-wide association dataset revealed that rs10012946, which is in strong linkage disequilibrium with the three WFS1 SNPs (r(2)=0.88-1.0), was associated with type 2 diabetes (allelic odds ratio 0.85, 95% CI 0.75-0.97, p=0.026). 18060660

2008

dbSNP: rs1024611
rs1024611
0.010 GeneticVariation BEFREE Multivariate Cox regression analysis, taking into the account the recipient's sex, age and BMI, as well as the number of G alleles of the CCL2 rs1024611 polymorphism, revealed that this polymorphism is an independent risk factor for post-transplant diabetes. 26802601

2016

dbSNP: rs10401969
rs10401969
0.700 GeneticVariation GWASCAT Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases. 27790247

2016

dbSNP: rs1042615
rs1042615
0.010 GeneticVariation BEFREE The rs1042615 T allele is associated with features resembling the phenotype of the V1aR(-/-) mouse, including uncoupling of the usual direct relation between glucose and triglycerides and an increased prevalence of diabetes in subjects with a high fat intake or who are overweight. 19056558

2009

dbSNP: rs1042714
rs1042714
0.010 GeneticVariation BEFREE Gln27Glu variant of the beta2-adrenergic receptor gene is not associated with obesity and diabetes in Japanese-Americans. 11288039

2001

dbSNP: rs1044250
rs1044250
0.010 GeneticVariation BEFREE We genotyped 629 subjects with and without a family history of diabetes for the 4 single nucleotide polymorphisms (SNPs) rs4076317, rs2278236, rs1044250, and rs11672433 and performed correlational analyses with metabolic traits. 18442626

2008

dbSNP: rs10455872
rs10455872
LPA
0.010 GeneticVariation BEFREE Lp(a) concentrations, apo(a) phenotypes, and one SNP in the LPA gene (rs10455872) were measured in the CAVASIC study, including 241 male patients with intermittent claudication and 246 age- and diabetes-matched controls as well as in the two population-based studies KORA F3 (n = 3184) and KORA F4 (n = 3080). 24760552

2015

dbSNP: rs10462020
rs10462020
0.010 GeneticVariation BEFREE Among these was a missense polymorphism (rs10462020; Gly639Val) in the clock gene PER3, a system recently implicated in diabetes. 21647700

2011

dbSNP: rs10486567
rs10486567
0.010 GeneticVariation BEFREE The JAZF1 SNPs rs6968704 and rs10486567 were associated with decreased risk of prostate cancer but were not associated with diabetes. 19998368

2010

dbSNP: rs10489177
rs10489177
0.010 GeneticVariation BEFREE The rs10489177 GG genotype was associated with significantly increased risk for IS in individuals without hypertension (OR = 2.78, 95 % CI = 1.59-4.86) and in individuals without diabetes (OR = 1.93, 95 % CI = 1.27-2.94). 24122314

2014

dbSNP: rs104894014
rs104894014
GCK
0.010 GeneticVariation BEFREE The second activating glucokinase mutation (A456V): implications for glucose homeostasis and diabetes therapy. 11916951

2002

dbSNP: rs1049353
rs1049353
0.010 GeneticVariation BEFREE A total of 1,064 obese subjects (BMI > or = 30 kg/m2) without diabetes, impaired glucose tolerance or other endocrine diseases and 251 healthy control persons were genotyped for the G1422A variant (rs1049353) with a TaqMan assay. 17873324

2007

dbSNP: rs10494366
rs10494366
0.010 GeneticVariation BEFREE We have independently replicated the association between rs10494366 in NOS1AP and incident diabetes among white CCB users. 19943157

2010

dbSNP: rs10497721
rs10497721
0.700 GeneticVariation GWASCAT Genome-wide association with diabetes-related traits in the Framingham Heart Study. 17903298

2007

dbSNP: rs1050450
rs1050450
0.010 GeneticVariation BEFREE Association between the rs1050450 glutathione peroxidase-1 (C > T) gene variant and peripheral neuropathy in two independent samples of subjects with diabetes mellitus. 21185702

2012

dbSNP: rs10509291
rs10509291
0.010 GeneticVariation BEFREE Among metabolically characterized subjects with normal glucose tolerance (N=243), those carrying the diabetes risk allele (T) for rs10509291 and (G) for rs7896005 had a reduced acute insulin response (AIR) to an intravenous glucose bolus (adjusted P=0.045 and 0.035, respectively). 21871827

2012

dbSNP: rs1051931
rs1051931
0.010 GeneticVariation BEFREE Lp-PLA2 activity and PLA2G7 A379V genotype in patients with diabetes mellitus. 16438975

2007

dbSNP: rs1055419
rs1055419
0.010 GeneticVariation BEFREE Significant associations between rs1055419 and diastolic blood pressure (OR = 0.53; P = 0.01) were found whereas IVS12+95 T>C, a newly discovered SNP, was associated with low-density lipoprotein-cholesterol levels (OR = 1.63; P < 0.001), hyperglycemia/diabetes (OR = 1.48; P < 0.004) as well as with MetS per se (OR = 1.56; P < 0.01). 19325544

2009

dbSNP: rs1057293
rs1057293
0.010 GeneticVariation BEFREE In additive models adjusted for hypertension, smoking and diabetes, the major allele (G) of rs1057293 was associated (odds ratio, 95% confidence interval; P value) with ischaemic stroke with similar effect size in both studies; in Lund (1.35, 1.11-1.64; P=0.002) and Malmö (1.30, 1.03-1.65; P=0.027). 21430556

2011

dbSNP: rs1057518903
rs1057518903
0.700 CausalMutation CLINVAR Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology. 25741868

2015

dbSNP: rs1060499866
rs1060499866
0.010 GeneticVariation BEFREE The HNF1A mutant Ala180Val: Clinical challenges in determining causality of a rare HNF1A variant in familial diabetes. 28934671

2018

dbSNP: rs1061170
rs1061170
CFH
0.010 GeneticVariation BEFREE The common Y402H variant in the CFH gene was not associated with classical cardiovascular risk factors (diabetes, hypercholesterolaemia, hypertension, obesity, smoking and C-reactive protein serum levels). 17472578

2007

dbSNP: rs10636
rs10636
0.010 GeneticVariation BEFREE Using the PCR-based restriction fragment length polymorphism method, seven single nucleotide polymorphisms (SNPs) in MT genes (rs8052394 and rs11076161 in MT1A gene, rs8052334, rs964372, and rs7191779 in MT1B gene, rs708274 in MT1E gene, and rs10636 in MT2A gene) were detected in 851 Chinese people of Han descent (397 diabetes and 454 controls). 18349110

2008

dbSNP: rs1063856
rs1063856
VWF
0.010 GeneticVariation BEFREE Three known vWF gene polymorphisms were genotyped in a group of 493 type I diabetic subjects, all showing proliferative retinopathy, but with various stages of renal involvement, which ranged from no microalbuminuria, despite a mean duration of diabetes of 31 years, to advanced nephropathy (GENEDIAB Study): Thr789Ala (Rsa I), M-/M+ (Msp I) (intron 19), and Ala1381Thr (Hph I). 10760079

2000