|
rs1333049
|
|
|
0.740 |
GeneticVariation |
BEFREE |
Genotype CC of rs1333049 was significantly associated with both elevated CRP levels and decreased HDL concentrations after univariate (p = 0.028, p = 0.012) and multivariate analysis (p = 0.041, p = 0.023) stratified for age, gender, body mass index, smoking, diabetes, and severe periodontitis.
|
31770616 |
2020 |
|
rs1333049
|
|
|
0.740 |
GeneticVariation |
GWASCAT |
Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
|
27790247 |
2016 |
|
rs1333049
|
|
|
0.740 |
GeneticVariation |
BEFREE |
Genotyping of variant rs1333049 on chromosome 9p21.3 was performed in 2387 patients with and without diabetes who were undergoing coronary angiography to evaluate suspected or established CAD.
|
21362310 |
2011 |
|
rs780094
|
|
|
0.740 |
GeneticVariation |
BEFREE |
This study provides the first evidence that GCKR rs780094, a single-nucleotide polymorphism related to diabetes, may be associated with pancreatic cancer risk.
|
22015968 |
2012 |
|
rs780094
|
|
|
0.740 |
GeneticVariation |
BEFREE |
The intronic single-nucleotide polymorphism (SNP) rs780094 (intron 16) and the missense SNP rs1260326 (P446L) in the GCKR gene are strongly associated with increased circulating triglyceride and C-reactive protein levels and, paradoxically, reductions in diabetes incidence, fasting glucose levels, and insulin resistance.
|
21525158 |
2011 |
|
rs780094
|
|
|
0.740 |
GeneticVariation |
GWASCAT |
Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
|
27790247 |
2016 |
|
rs780094
|
|
|
0.740 |
GeneticVariation |
BEFREE |
Our findings indicate rs780094 has independent associations with multiple metabolic traits as well as incident diabetes, but not incident CHD or stroke.
|
20661421 |
2010 |
|
rs780094
|
|
|
0.740 |
GeneticVariation |
BEFREE |
In the Danish MONICA study four gene variants were significantly associated with incident CVD independently of known diabetes status at baseline; SLC2A2 rs11920090 (HR 1.147, 95% CI 1.027-1.283 , P = 0.0154), C2CD4A rs7172432 (1.112, 1.027-1.205 , P = 0.0089), GCKR rs780094 (1.094, 1.007-1.188 , P = 0.0335) and C2CD4B rs11071657 (1.092, 1.007-1.183 , P = 0.0323).
|
23185617 |
2012 |
|
rs587783672
|
|
|
0.720 |
GeneticVariation |
BEFREE |
At follow-up of the TNDM patients with genetic alterations, 43% developed diabetes or impaired glucose tolerance in later life (one with 6q24 duplication and two with N48D and E227K mutations at KCNJ11 gene).
|
17490422 |
2007 |
|
rs587783672
|
|
|
0.720 |
GeneticVariation |
BEFREE |
Only one mutation (p.Glu227Lys in KCNJ11) co-segregated with diabetes in the family (with a LOD-score of 3.68).
|
22701567 |
2012 |
|
rs13333226
|
|
|
0.710 |
GeneticVariation |
BEFREE |
The G allele of rs13333226 was associated with a decreased risk of nephropathy [odds ratio (OR) 0.80, 95% confidence interval (CI) 0.69-0.91, P = 0.001] after correction for confounding factors like age, sex, body mass index (BMI), blood pressure, kidney function, smoking and duration of diabetes.
|
21738052 |
2011 |
|
rs13333226
|
|
|
0.710 |
GeneticVariation |
GWASCAT |
A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes.
|
29703844 |
2018 |
|
rs193929355
|
|
|
0.710 |
GeneticVariation |
BEFREE |
Nineteen children carrying KCNJ11 mutations associated with isolated diabetes (R201H; n = 8), diabetes with neurodevelopmental impairment (V59M or V59A [V59M/A]; n = 8), or diabetes not consistently associated with neurodevelopmental disability (Y330C, E322K, or R201C; n = 3) were studied using the age-standardized Beery-Buktenica Developmental Test of Visual-Motor Integration (VMI).
|
22855734 |
2012 |
|
rs4420638
|
|
|
0.710 |
GeneticVariation |
BEFREE |
Following regression analysis adjusted by collection center, gender, duration of diabetes, and average HbA1c, two SNPs were significantly associated with DN. rs4420638 in the APOC1 region (odds ratio [OR] = 1.51; confidence intervals [CI]: 1.19-1.91; P = 0.001) and rs1532624 in CETP (OR = 0.82; CI: 0.69-0.99; P = 0.034); rs4420638 was also significantly associated in a sensitivity analysis (P = 0.016) together with rs7679 (P = 0.027).
|
23555584 |
2013 |
|
rs4420638
|
|
|
0.710 |
GeneticVariation |
GWASCAT |
Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
|
27790247 |
2016 |
|
rs80356625
|
|
|
0.710 |
GeneticVariation |
BEFREE |
Five different heterozygous mutations were identified: c.149G>C (p.R50P), c.175G>A (p.V59M), c.509A>G (p.K170R), c.510G>C (p.K170N), and c.601C>T (p.R201C) in eight patients with diabetes diagnosed between day 3 and 182.
|
15580558 |
2005 |
|
rs10084572
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program.
|
31451708 |
2019 |
|
rs10224002
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes.
|
29703844 |
2018 |
|
rs10224210
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program.
|
31451708 |
2019 |
|
rs10401969
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
|
27790247 |
2016 |
|
rs1047891
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program.
|
31451708 |
2019 |
|
rs10497721
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association with diabetes-related traits in the Framingham Heart Study.
|
17903298 |
2007 |
|
rs10811652
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association study of coronary artery disease among individuals with diabetes: the UK Biobank.
|
30003307 |
2018 |
|
rs10941191
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program.
|
31451708 |
2019 |
|
rs11124945
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association study identifies pharmacogenomic loci linked with specific antihypertensive drug treatment and new-onset diabetes.
|
27670767 |
2018 |