Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs13333226
rs13333226
UMOD
0.710 GeneticVariation BEFREE The G allele of rs13333226 was associated with a decreased risk of nephropathy [odds ratio (OR) 0.80, 95% confidence interval (CI) 0.69-0.91, P = 0.001] after correction for confounding factors like age, sex, body mass index (BMI), blood pressure, kidney function, smoking and duration of diabetes. 21738052

2011
dbSNP: rs13333226
rs13333226
UMOD
0.710 GeneticVariation GWASCAT A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes. 29703844

2018
dbSNP: rs193929355
rs193929355
KCNJ11
0.710 GeneticVariation BEFREE Nineteen children carrying KCNJ11 mutations associated with isolated diabetes (R201H; n = 8), diabetes with neurodevelopmental impairment (V59M or V59A [V59M/A]; n = 8), or diabetes not consistently associated with neurodevelopmental disability (Y330C, E322K, or R201C; n = 3) were studied using the age-standardized Beery-Buktenica Developmental Test of Visual-Motor Integration (VMI). 22855734

2012
dbSNP: rs4420638
rs4420638
APOC1
0.710 GeneticVariation BEFREE Following regression analysis adjusted by collection center, gender, duration of diabetes, and average HbA1c, two SNPs were significantly associated with DN. rs4420638 in the APOC1 region (odds ratio [OR] = 1.51; confidence intervals [CI]: 1.19-1.91; P = 0.001) and rs1532624 in CETP (OR = 0.82; CI: 0.69-0.99; P = 0.034); rs4420638 was also significantly associated in a sensitivity analysis (P = 0.016) together with rs7679 (P = 0.027). 23555584

2013
dbSNP: rs4420638
rs4420638
APOC1
0.710 GeneticVariation GWASCAT Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases. 27790247

2016
dbSNP: rs80356625
rs80356625
KCNJ11
0.710 GeneticVariation BEFREE Five different heterozygous mutations were identified: c.149G>C (p.R50P), c.175G>A (p.V59M), c.509A>G (p.K170R), c.510G>C (p.K170N), and c.601C>T (p.R201C) in eight patients with diabetes diagnosed between day 3 and 182. 15580558

2005
dbSNP: rs10084572
rs10084572
LOC105372829
T 0.700 GeneticVariation GWASCAT Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program. 31451708

2019
dbSNP: rs10224002
rs10224002
PRKAG2
A 0.700 GeneticVariation GWASCAT A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes. 29703844

2018
dbSNP: rs10224210
rs10224210
PRKAG2
T 0.700 GeneticVariation GWASCAT Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program. 31451708

2019
dbSNP: rs10401969
rs10401969
SUGP1
0.700 GeneticVariation GWASCAT Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases. 27790247

2016
dbSNP: rs1047891
rs1047891
CPS1
A 0.700 GeneticVariation GWASCAT Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program. 31451708

2019
dbSNP: rs10497721
rs10497721
TMEFF2 ; LOC101927366
0.700 GeneticVariation GWASCAT Genome-wide association with diabetes-related traits in the Framingham Heart Study. 17903298

2007
dbSNP: rs10811652
rs10811652
CDKN2B-AS1
C 0.700 GeneticVariation GWASCAT Genome-wide association study of coronary artery disease among individuals with diabetes: the UK Biobank. 30003307

2018
dbSNP: rs10941191
rs10941191 		A 0.700 GeneticVariation GWASCAT Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program. 31451708

2019
dbSNP: rs11124945
rs11124945
PLEKHH2
G 0.700 GeneticVariation GWASCAT Genome-wide association study identifies pharmacogenomic loci linked with specific antihypertensive drug treatment and new-onset diabetes. 27670767

2018
dbSNP: rs113296370
rs113296370
PLEKHH2
C 0.700 GeneticVariation GWASCAT Genome-wide association study identifies pharmacogenomic loci linked with specific antihypertensive drug treatment and new-onset diabetes. 27670767

2018
dbSNP: rs1135401784
rs1135401784
CP
G 0.700 GeneticVariation CLINVAR

dbSNP: rs11622435
rs11622435
LOC101928462
0.700 GeneticVariation GWASCAT A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes. 29703844

2018
dbSNP: rs11864909
rs11864909
PDILT
T 0.700 GeneticVariation GWASCAT A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes. 29703844

2018
dbSNP: rs12310617
rs12310617 		0.700 GeneticVariation GWASCAT Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases. 27790247

2016
dbSNP: rs12369179
rs12369179
ZCCHC8
0.700 GeneticVariation GWASCAT Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases. 27790247

2016
dbSNP: rs12420422
rs12420422 		0.700 GeneticVariation GWASCAT Specifically, from Group 2, we find rs7632505 on 3q21.1 in <i>SEMA5B</i>, rs460976 on 21q22.3 (1 kb from <i>TMPRSS2</i>) and rs12420422 on 11q24.1 predominantly associated with a variety of CVDs, rs4905014 in <i>ITPK1</i> associated with stroke and heart failure, rs7081476 on 10p12.1 in <i>ANKRD26</i> associated with multiple diseases including DM, CVDs, and NDs. 27790247

2016
dbSNP: rs12579302
rs12579302
ATP2B1
0.700 GeneticVariation GWASCAT Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases. 27790247

2016
dbSNP: rs1264347
rs1264347
LINC00243
T 0.700 GeneticVariation GWASCAT Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program. 31451708

2019
dbSNP: rs12917707
rs12917707
UMOD
T 0.700 GeneticVariation GWASCAT Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. 26831199

2016