|
rs1044250
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We genotyped 629 subjects with and without a family history of diabetes for the 4 single nucleotide polymorphisms (SNPs) rs4076317, rs2278236, rs1044250, and rs11672433 and performed correlational analyses with metabolic traits.
|
18442626 |
2008 |
|
rs1044498
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We assessed rs1044498 (K173Q) located in the ENPP1 gene for association with diabetes nephropathy among 201 diabetic subjects without nephropathy and 215 diabetic subjects with nephropathy in the Taiwanese population.
|
21198320 |
2011 |
|
rs10455872
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We tested associations of tertiles of lipoprotein(a) concentration in plasma and two LPA single-nucleotide polymorphisms ([SNPs] rs10455872 and rs3798220) with all-cause mortality and cardiovascular mortality by Cox regression analysis and with severity of disease by generalised linear modelling, with and without adjustment for age, sex, diabetes diagnosis, systolic blood pressure, BMI, smoking status, estimated glomerular filtration rate, LDL-cholesterol concentration, and use of lipid-lowering therapy.
|
28566218 |
2017 |
|
rs1047891
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program.
|
31451708 |
2019 |
|
rs10484821
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The genome-wide association study identified 26 SNPs associated with new-onset diabetes after transplantation; this association was validated for eight SNPs (rs10484821, rs7533125, rs2861484, rs11580170, rs2020902, rs1836882, rs198372, and rs4394754) by de novo genotyping.
|
24309190 |
2014 |
|
rs10486567
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The JAZF1 SNPs rs6968704 and rs10486567 were associated with decreased risk of prostate cancer but were not associated with diabetes.
|
19998368 |
2010 |
|
rs10489177
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs10489177 GG genotype was associated with significantly increased risk for IS in individuals without hypertension (OR = 2.78, 95 % CI = 1.59-4.86) and in individuals without diabetes (OR = 1.93, 95 % CI = 1.27-2.94).
|
24122314 |
2014 |
|
rs104894014
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The second activating glucokinase mutation (A456V): implications for glucose homeostasis and diabetes therapy.
|
11916951 |
2002 |
|
rs1049353
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A total of 1,064 obese subjects (BMI > or = 30 kg/m2) without diabetes, impaired glucose tolerance or other endocrine diseases and 251 healthy control persons were genotyped for the G1422A variant (rs1049353) with a TaqMan assay.
|
17873324 |
2007 |
|
rs10494366
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We have independently replicated the association between rs10494366 in NOS1AP and incident diabetes among white CCB users.
|
19943157 |
2010 |
|
rs10494366
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In our study, the meta-analysis displayed the GG genotype of rs10494366 correlated with the QT interval in women with no heterogeneity, and in diabetes mellitus (DM) patients with minor heterogeneity.
|
31447468 |
2019 |
|
rs10497721
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association with diabetes-related traits in the Framingham Heart Study.
|
17903298 |
2007 |
|
rs1050450
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This is the first paper to examine the rs1050450 variant in two samples of Caucasian subjects with diabetes.
|
21185702 |
2012 |
|
rs1050828
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A recently published example is the erythrocytic variant (rs1050828) in G6PD, which leads to the artificial lowering of HbA1c and missed diagnosis of diabetes using current thresholds.
|
29522974 |
2018 |
|
rs10509291
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Among metabolically characterized subjects with normal glucose tolerance (N=243), those carrying the diabetes risk allele (T) for rs10509291 and (G) for rs7896005 had a reduced acute insulin response (AIR) to an intravenous glucose bolus (adjusted P=0.045 and 0.035, respectively).
|
21871827 |
2011 |
|
rs10517086
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three single nucleotide polymorphisms were associated with increased diabetes risk (rs10517086_A [<i>P</i> = 0.03], rs1534422_G [<i>P</i> = 0.006], and rs2327832_G [<i>P</i> = 0.03] in <i>TNFAIP3</i>) and one with decreased risk (rs1004446_A in <i>INS</i> [<i>P</i> = 0.006]).
|
28903990 |
2017 |
|
rs1051931
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Lp-PLA2 activity and PLA2G7 A379V genotype in patients with diabetes mellitus.
|
16438975 |
2006 |
|
rs1052133
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The association of the Ser326Cys polymorphism in the 8-oxoguanine glycosylase (OGG1) gene with a colon carcinoma and diabetes mellitus has been examined.
|
23368532 |
2013 |
|
rs1052700
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The PLIN polymorphisms significantly interacted with central obesity in relation to diabetes risk (P for interaction = 0.036, 0.033, and 0.042 for rs1052700, rs894160, and rs2304796, respectively).
|
23517113 |
2013 |
|
rs1056534
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, this is the first study describing significant relationship of FN3K (rs1056534) and (rs3848403) polymorphisms with concentration of sRAGE in patients with diabetes.
|
24908234 |
2014 |
|
rs1057293
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In additive models adjusted for hypertension, smoking and diabetes, the major allele (G) of rs1057293 was associated (odds ratio, 95% confidence interval; P value) with ischaemic stroke with similar effect size in both studies; in Lund (1.35, 1.11-1.64; P=0.002) and Malmö (1.30, 1.03-1.65; P=0.027).
|
21430556 |
2011 |
|
rs1057515576
|
|
GAAAA |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs1057518903
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs1057520291
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Herein, we present a child who was diagnosed with CHI at birth, then developed diabetes mellitus at the age of nine years due to a novel homozygous missense, p.L171F (c.511C>T) mutation in exon 4 of <i>ABCC8</i>.
|
29739729 |
2019 |
|
rs1057520504
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We also observed cosegregation with diabetes of the Arg263His coding region mutation in eight members of one MODY family, whereas it was absent in nondiabetic subjects of this family.
|
19336507 |
2009 |