|
rs2476601
|
|
|
1.000 |
GeneticVariation |
UNIPROT |
|
|
|
|
rs1307997067
|
|
G |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs137853236
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs1555212014
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs28934906
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs397507478
|
|
A |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs587776825
|
|
GC |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs587780357
|
|
A |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs754729248
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs782511378
|
|
A |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs61839660
|
|
|
0.800 |
GeneticVariation |
GWASCAT |
1000 Genomes-based imputation identifies novel and refined associations for the Wellcome Trust Case Control Consortium phase 1 Data.
|
22293688 |
2012 |
|
rs61839660
|
|
|
0.800 |
GeneticVariation |
GWASDB |
1000 Genomes-based imputation identifies novel and refined associations for the Wellcome Trust Case Control Consortium phase 1 Data.
|
22293688 |
2012 |
|
rs2111485
|
|
|
0.710 |
GeneticVariation |
BEFREE |
Islet autoantibody-positive children with the IFIH1 rs2111485 GG genotype had a faster progression to diabetes (31% within 5 years) than children with the type 1 diabetes protective GA or AA genotypes (11% within 5 years; P = 0.006).
|
21270278 |
2011 |
|
rs1801262
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Ala45Thr and Pro197His were not associated with type 2 diabetes, but the transmission disequilibrium test showed unequal transmission of the A45 allele to offspring with type 1 diabetes (chi2 = 5.90, P < 0.02, odds ratio 1.55, 95% CI 0.91-2.63).
|
10905500 |
2000 |
|
rs237025
|
|
|
0.100 |
GeneticVariation |
BEFREE |
M55V variant of SUMO4 was significantly associated with type 1 diabetes in Asians, but genetic heterogeneity between Asian and Caucasian populations was suggested.
|
17130532 |
2006 |
|
rs370443546
|
|
|
0.020 |
GeneticVariation |
BEFREE |
M55V variant of SUMO4 was significantly associated with type 1 diabetes in Asians, but genetic heterogeneity between Asian and Caucasian populations was suggested.
|
17130532 |
2006 |
|
rs2903692
|
|
|
0.840 |
GeneticVariation |
BEFREE |
rs2903692 conferred a protective effect on patients with T1D, MS and RA.
|
19221398 |
2010 |
|
rs601338
|
|
|
0.010 |
GeneticVariation |
BEFREE |
rs601338A>G was genotyped in 8,344 patients with ty</span>pe 1 diabetes, 10,008 control subjects, and 3,360 type 1 diabetic families.
|
22025780 |
2011 |
|
rs11203203
|
|
|
0.810 |
GeneticVariation |
BEFREE |
rs11203203 is associated with type 1 diabetes risk in population pre-screened for high-risk HLA-DR,DQ genotypes.
|
22776074 |
2012 |
|
rs2476601
|
|
|
1.000 |
GeneticVariation |
BEFREE |
C1858T Polymorphism of Protein Tyrosine Phosphatase Non-receptor Type 22 (PTPN22): an eligible target for prevention of type 1 diabetes?
|
27892782 |
2017 |
|
rs237025
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A M55V polymorphism in a novel SUMO gene (SUMO-4) differentially activates heat shock transcription factors and is associated with susceptibility to type I diabetes mellitus.
|
15123604 |
2004 |
|
rs760160309
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A M55V polymorphism in a novel SUMO gene (SUMO-4) differentially activates heat shock transcription factors and is associated with susceptibility to type I diabetes mellitus.
|
15123604 |
2004 |
|
rs2476601
|
|
|
1.000 |
GeneticVariation |
BEFREE |
A C1858T single nucleotide polymorphism within PTPN22 (which encodes PTPN22<sup>R620W</sup>) is associated with an enhanced susceptibility to multiple autoimmune diseases including type 1 diabetes and rheumatoid arthritis.
|
30139951 |
2018 |
|
rs2476601
|
|
|
1.000 |
GeneticVariation |
BEFREE |
A coding variant in PTPN22 (C1858T) is one of the most important genetic risk factors in type 1 diabetes (T1D).
|
31732921 |
2020 |
|
rs1801278
|
|
|
0.030 |
GeneticVariation |
BEFREE |
A collection of 767 multiplex type 1 diabetes families from the US and UK were tested for linkage to the IRS1 gene and for allelic association with a specific variant of IRS1, G972R.
|
15059616 |
2004 |