rs10011025
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In this study, the association between the common rs10011025 variant in the GLRA3 locus, and albuminuria, was confirmed in 1259 independent Finnish individuals with type 1 diabetes (p = 0.0013), and meta-analysis of all Finnish individuals yielded a genome-wide significant association.
|
30120300 |
2018 |
rs1001179
|
|
|
0.020 |
GeneticVariation |
BEFREE |
There was no significant association between the CAT gene SNP rs1001179 and T1D or DPN.
|
29924645 |
2018 |
rs1001179
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Major effects of two SNPs, C1167T (rs769217) and C(-262)T (rs1001179), of the catalase gene on T1D susceptibility have been reported previously in Russians from Moscow.
|
16453382 |
2006 |
rs1003878
|
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene.
|
17632545 |
2007 |
rs1004446
|
|
C |
0.810 |
GeneticVariation |
GWASDB |
A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene.
|
17632545 |
2007 |
rs1004446
|
|
C |
0.810 |
GeneticVariation |
GWASCAT |
A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene.
|
17632545 |
2007 |
rs1004446
|
|
|
0.810 |
GeneticVariation |
BEFREE |
Characteristics included are age at multiple autoantibody positivity, sex, selected high-risk HLA-DR-DQ genotypes, relationship to a family member with T1D, autoantibody at seroconversion, <i>INS</i> gene (rs1004446_A), and non-HLA gene polymorphisms identified by the Type 1 Diabetes Genetics Consortium (T1DGC).
|
28903990 |
2017 |
rs1004446
|
|
G |
0.810 |
GeneticVariation |
GWASCAT |
Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases.
|
21829393 |
2011 |
rs1012411
|
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene.
|
17632545 |
2007 |
rs1015166
|
|
T |
0.800 |
GeneticVariation |
GWASCAT |
Genome wide identification of new genes and pathways in patients with both autoimmune thyroiditis and type 1 diabetes.
|
25936594 |
2015 |
rs1015166
|
|
|
0.800 |
GeneticVariation |
GWASDB |
A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene.
|
17632545 |
2007 |
rs10181656
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The analysis of genotypes and haplotypes of the same SNPs (rs7574865, rs8179673, and rs10181656) showed very comparable degrees of risk for T1D.
|
19120275 |
2008 |
rs10186193
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SNP rs10186193 (at RNASEH1 gene) showed association with T1D (P = 0.005).
|
29204916 |
2018 |
rs1020856343
|
|
|
0.010 |
GeneticVariation |
BEFREE |
For these reasons, we investigated for the first time the association with T1D of six single nucleotide polymorphisms (SNPs) mapping to these candidate genes: slc2F2, slc2F11, T306I, L503F, OCTN2-promoter and OCTN2-intron.
|
16796743 |
2006 |
rs1022059218
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The 49A/G dimorphism in exon 1 and the (AT)n in the 3' untranslated region of the CTLA-4 gene were significantly associated with type 1 diabetes.
|
11685455 |
2001 |
rs1023934247
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Typing for HLA-DQA1 and DQB1 alleles showed that type 1 diabetes-predisposing DQ alpha/DQ beta heterodimers were less frequent in patients carrying N252S or P477A than in those carrying wild-type PRF1.
|
18198357 |
2008 |
rs10255021
|
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene.
|
17632545 |
2007 |
rs10272724
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The minor allele of rs10272724 (C) was found to be protective from type 1 diabetes (odds ratio 0.87 [95% CI 0.83-0.91]; P = 1.1 × 10(-11)). rs10272724 was not correlated with levels of two transcripts of IKZF1 in peripheral blood mononuclear cells.
|
21270240 |
2011 |
rs10277986
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers.
|
25751624 |
2015 |
rs10336
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A combination of a case (n = 447)-control (n = 300) and family (n = 221) analysis was performed to investigate the role of the CXCL9 (rs10336, rs3733236) and CXCL10 (rs3921, rs35795399 and rs8878) polymorphisms and their interaction with HLA high-risk haplotypes DQ2(DQA*0501-DQB*0201)-DQ8(DQA*0301-DQB*0302) in T1D.
|
19410617 |
2009 |
rs1041740
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Further studies are necessary to assess the relationship between rs1041740 and T1D or DPN.
|
29924645 |
2018 |
rs1041981
|
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene.
|
17632545 |
2007 |
rs1042713
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We performed genotyping of the A265G (Arg16Gly) polymorphism in the ADRB2 gene in 85 patients with type 1 diabetes and classified them according to hypoglycemia awareness status.
|
18334922 |
2008 |
rs10484566
|
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene.
|
17632545 |
2007 |
rs1048990
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To fulfil this gap, single nucleotide polymorphisms in the PSMB5 (rs11543947), PSMA6 (rs2277460, rs1048990), PSMC6 (rs2295826, rs2295827) and PSMA3 (rs2348071) genes were genotyped on susceptibility to T1DM in Latvians.
|
26661414 |
2016 |