Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.090 | GeneticVariation | BEFREE | A meta-analysis assessed whether the Ala45Thr polymorphism of the neurogenic differentiation 1 (NEUROD1) gene is associated with increased risk of diabetes mellitus type 1 (T1D) or type 2 (T2D). | 15592940 | 2005 |
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0.090 | GeneticVariation | BEFREE | We found a gender-specific association of the Ala45Thr variant of NEUROD1 with Type 1 diabetes in Brazilian women. | 16357810 | 2005 |
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0.090 | GeneticVariation | BEFREE | Lack of association of the Ala(45)Thr polymorphism and other common variants of the NeuroD gene with type 1 diabetes. | 15047635 | 2004 |
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0.090 | GeneticVariation | BEFREE | The Ala45Thr polymorphism of BETA2/NeuroD1 gene and susceptibility to type 1 diabetes mellitus in caucasians. | 12951629 | 2003 |
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0.090 | GeneticVariation | BEFREE | Our results confirm that the NEUROD Ala45Thr polymorphism is associated with childhood-onset Type 1 DM. | 12639765 | 2003 |
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0.090 | GeneticVariation | BEFREE | Ala45Thr and Pro197His were not associated with type 2 diabetes, but the transmission disequilibrium test showed unequal transmission of the A45 allele to offspring with type 1 diabetes (chi2 = 5.90, P < 0.02, odds ratio 1.55, 95% CI 0.91-2.63). | 10905500 | 2000 |
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0.090 | GeneticVariation | BEFREE | Our present results do not support a recent report which described an association of the Ala45Thr variant with type 1 diabetes in Japanese. | 10808064 | 2000 |
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0.090 | GeneticVariation | BEFREE | Because the variant of the NeuroD/BETA2 gene (Ala45Thr) is associated with type 1 but not type 2 diabetes, it may be implicated in the loss of pancreatic beta-cells in type 1 diabetes. | 10334323 | 1999 |
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0.090 | GeneticVariation | BEFREE | Recently, a significant association has been reported between NEUROD1-A45T polymorphism and Type 1 diabetes in the Japanese population. | 10633878 | 1999 |