Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs478582
rs478582
0.040 GeneticVariation BEFREE Our results suggest that rs1893217 may increase the risk of early-onset T1D and affect humoral immunity, while rs478582 may affect Treg subsets. 31030572

2019

dbSNP: rs478582
rs478582
0.040 GeneticVariation BEFREE No difference was observed in association of rs478582 in The PTPN2 gene and T1DM. 26344020

2015

dbSNP: rs478582
rs478582
0.040 GeneticVariation BEFREE Of the 1692 DAISY children genotyped for VDR rs1544410, VDR rs2228570, VDR rs11568820, PTPN2 rs1893217, and PTPN2 rs478582, 111 developed IA, defined as positivity for GAD, insulin or IA-2 autoantibodies on 2 or more consecutive visits, and 38 IA positive children progressed to T1D. 22960018

2013

dbSNP: rs478582
rs478582
0.040 GeneticVariation BEFREE We genotyped 439 T1D Spanish subjects (age at onset, 1 to 65 years) and 861 controls for two PTPN2 single nucleotide polymorphisms (SNPs), rs2542151 and rs478582, and studied the effect of both polymorphisms in age at onset through stratified and continuous analyses. 21246196

2011