Variant Gene Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs200998587
rs200998587
0.700 SusceptibilityMutation CLINVAR

dbSNP: rs76474829
rs76474829
0.700 SusceptibilityMutation CLINVAR

dbSNP: rs948820149
rs948820149
0.700 GeneticVariation CLINVAR

dbSNP: rs104894008
rs104894008
0.010 GeneticVariation BEFREE Here we report the isolation and partial sequence of the human glucokinase gene and the identification of two missense mutations in exon 7, Thr-228----Met and Gly-261----Arg, that cosegregate with early-onset non-insulin-dependent diabetes mellitus. 1502186

1992

dbSNP: rs121434581
rs121434581
0.700 GeneticVariation UNIPROT Insulin receptor and insulin-responsive glucose transporter (GLUT 4) mutations and polymorphisms in a Welsh type 2 (non-insulin-dependent) diabetic population. 1521731

1992

dbSNP: rs121913150
rs121913150
0.800 GeneticVariation UNIPROT NIDDM associated with mutation in tyrosine kinase domain of insulin receptor gene. 1607076

1992

dbSNP: rs121913150
rs121913150
0.800 CausalMutation CLINVAR NIDDM associated with mutation in tyrosine kinase domain of insulin receptor gene. 1607076

1992

dbSNP: rs121434581
rs121434581
0.700 GeneticVariation UNIPROT Molecular scanning of insulin-responsive glucose transporter (GLUT4) gene in NIDDM subjects. 1756912

1992

dbSNP: rs121434581
rs121434581
0.700 GeneticVariation UNIPROT Analysis of the gene sequences of the insulin receptor and the insulin-sensitive glucose transporter (GLUT-4) in patients with common-type non-insulin-dependent diabetes mellitus. 1918382

1991

dbSNP: rs1801483
rs1801483
0.800 GeneticVariation BEFREE None of the Japanese diabetic patients showed Gly40Ser mutation and the association of this mutation with NIDDM was significantly different (p < 4.10(-5) vs French, p < 3.10(-6) vs Sardinian by Fisher's exact test). 7589886

1995

dbSNP: rs4994
rs4994
0.100 GeneticVariation BEFREE Pima subjects homozygous for the Trp64Arg beta 3-adrenergic-receptor mutation have an earlier onset of NIDDM and tend to have a lower resting metabolic rate. 7609750

1995

dbSNP: rs4994
rs4994
0.100 GeneticVariation BEFREE The Trp64Arg allele of the beta 3-adrenergic receptor is associated with abdominal obesity and resistance to insulin and may contribute to the early onset of NIDDM: 7609751

1995

dbSNP: rs182552223
rs182552223
0.700 GeneticVariation UNIPROT Frequency of mutations of insulin receptor gene in Japanese patients with NIDDM. 7657032

1995

dbSNP: rs1801278
rs1801278
0.100 GeneticVariation BEFREE Our results suggest that the Gly972Arg polymorphism does not play an important role in the pathogenesis of NIDDM in Japanese patients. 7673430

1995

dbSNP: rs1801278
rs1801278
0.100 GeneticVariation BEFREE Two SSCP variants that change the sequence of the protein, delta S686/687 (deletion of the codons for serine-686 and 687) and G972R, were identified in two different NIDDM subjects, both whom were also heterozygous for the V101I polymorphisms in GLUT2. 7713316

1995

dbSNP: rs1801483
rs1801483
0.800 CausalMutation CLINVAR A missense mutation in the glucagon receptor gene is associated with non-insulin-dependent diabetes mellitus. 7773293

1995

dbSNP: rs1801278
rs1801278
0.100 GeneticVariation BEFREE The purpose of this study was to examine the role of the IRS-1 missense mutations at codons 972 (glycine to arginine) and 513 (alanine to proline) in two diverse populations from South India and Finland at high risk for NIDDM. 7796990

1995

dbSNP: rs1801276
rs1801276
0.030 GeneticVariation BEFREE The purpose of this study was to examine the role of the IRS-1 missense mutations at codons 972 (glycine to arginine) and 513 (alanine to proline) in two diverse populations from South India and Finland at high risk for NIDDM. 7796990

1995

dbSNP: rs121913150
rs121913150
0.800 CausalMutation CLINVAR Failure to detect Glut4-Ile383 and IR-Gln1152 variants in NIDDM (non-insulin dependent diabetes mellitus) and control subjects in an Italian population. 7814014

1995

dbSNP: rs2229621
rs2229621
HK2
0.020 GeneticVariation BEFREE Analysis of the hexokinase II gene in subjects with insulin resistance and NIDDM and detection of a Gln142-->His substitution. 7883122

1995

dbSNP: rs35449651
rs35449651
0.700 GeneticVariation UNIPROT Sequence of the human glycogen-associated regulatory subunit of type 1 protein phosphatase and analysis of its coding region and mRNA level in muscle from patients with NIDDM. 7926294

1994

dbSNP: rs121909741
rs121909741
0.010 GeneticVariation BEFREE A threonine 110-->isoleucine substitution was present at equal frequency in diabetic and control populations, and a valine 197-->isoleucine substitution was discovered in a single allele of a patient with non-insulin-dependent diabetes. 8027028

1994

dbSNP: rs5400
rs5400
0.010 GeneticVariation BEFREE A threonine 110-->isoleucine substitution was present at equal frequency in diabetic and control populations, and a valine 197-->isoleucine substitution was discovered in a single allele of a patient with non-insulin-dependent diabetes. 8027028

1994

dbSNP: rs768715144
rs768715144
LPL
0.010 GeneticVariation BEFREE A proband with chylomicronemia, pancreatitis, and non-insulin-dependent diabetes (NIDDM) bears two different mutations in exon 3 of the lipoprotein lipase (LPL) gene: a missense mutation, 75Arg-->Ser, inherited through the paternal line and a truncation, 73Tyr-->Ter, through the maternal line. 8325986

1993

dbSNP: rs1801483
rs1801483
0.800 CausalMutation CLINVAR Glucagon receptor gene mutation in essential hypertension. 8563746

1996