Variant Gene Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10010131
rs10010131
0.050 GeneticVariation BEFREE All the risk alleles in the 11 examined type 2 diabetes risk variants showed an odds ratio (OR) greater than 1 for the GDM group compared with the control group ranging from 1.13 [95% confidence interval (CI) 0.88-1.46] to 1.44 (95% CI 1.19-1.74) except for the WFS1 rs10010131 variant with OR 0.87 (95% CI 0.73-1.05). 18984664

2009

dbSNP: rs10010131
rs10010131
0.050 GeneticVariation BEFREE A total of 1,578 non-diabetic individuals (534 men and 1,044 women, aged 40 +/- 13 years, BMI 28.9 +/- 8.2 kg/m(2) [mean +/- SD]) at increased risk of type 2 diabetes were genotyped for rs10010131 within the WFS1 gene. 19330314

2009

dbSNP: rs10010131
rs10010131
0.050 GeneticVariation BEFREE Cox analyses showed an association between the G-allele of rs10010131 and incident type 2 diabetes (HR 1.34, 95% CI 1.08-1.70, p = 0.007). 21127832

2011

dbSNP: rs10010131
rs10010131
0.050 GeneticVariation BEFREE Nine variants in FTO rs8050136, WFS1 rs10010131, CDKN2A/B rs10811661, KCNJ11 rs5219, CDC123/CAMK1D rs12779790, JAZF1 rs864745, SLC30A8 rs13266634, CDKAL1 rs10946398, and HHEX/IDE rs5015480 were significantly associated with T2DM (P < 0.05). 23298195

2014

dbSNP: rs10010131
rs10010131
0.050 GeneticVariation BEFREE While FTO rs8050136 and rs17817449, ADAMTS9 rs4607103, and WFS1 rs10010131 were initially associated with T2DM, this was lost upon multiple testing correction. 24145053

2014

dbSNP: rs10012946
rs10012946
0.010 GeneticVariation BEFREE Examination of the publicly available Diabetes Genetics Initiative genome-wide association dataset revealed that rs10012946, which is in strong linkage disequilibrium with the three WFS1 SNPs (r(2)=0.88-1.0), was associated with type 2 diabetes (allelic odds ratio 0.85, 95% CI 0.75-0.97, p=0.026). 18060660

2008

dbSNP: rs1002630
rs1002630
0.010 GeneticVariation BEFREE This study showed that the rs1002630 of CHN2 were associated with DR risk and non-proliferative DR risk in Taiwanese individuals with type 2 diabetes. 24854763

2015

dbSNP: rs10034465
rs10034465
0.700 GeneticVariation GWASCAT Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes. 28736931

2018

dbSNP: rs1011754
rs1011754
0.700 GeneticVariation GWASDB Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. 22158537

2012

dbSNP: rs10146997
rs10146997
0.700 GeneticVariation GWASCAT An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans. 28566273

2017

dbSNP: rs1017568
rs1017568
0.700 GeneticVariation GWASCAT Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes. 28736931

2018

dbSNP: rs10189773
rs10189773
0.700 GeneticVariation GWASDB Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. 17463246

2007

dbSNP: rs10190052
rs10190052
0.800 GeneticVariation GWASCAT Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. 24509480

2014

dbSNP: rs10190052
rs10190052
0.800 GeneticVariation GWASDB Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. 24509480

2014

dbSNP: rs10195252
rs10195252
0.700 GeneticVariation GWASDB Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. 22885922

2012

dbSNP: rs10203174
rs10203174
0.800 GeneticVariation GWASCAT Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. 22885922

2012

dbSNP: rs10203174
rs10203174
0.800 GeneticVariation GWASDB Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. 22885922

2012

dbSNP: rs1020731
rs1020731
0.700 GeneticVariation GWASDB Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes. 20418489

2010

dbSNP: rs10229583
rs10229583
0.810 GeneticVariation BEFREE Our study identifies rs10229583 near PAX4 as a novel locus for type 2 diabetes in Chinese and other populations and provides new insights into the pathogenesis of type 2 diabetes. 23532257

2013

dbSNP: rs10229583
rs10229583
0.810 GeneticVariation GWASCAT Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4. 23532257

2013

dbSNP: rs10229583
rs10229583
0.810 GeneticVariation GWASDB Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4. 23532257

2013

dbSNP: rs10244051
rs10244051
0.700 GeneticVariation GWASDB Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. 22158537

2012

dbSNP: rs10247649
rs10247649
0.010 GeneticVariation BEFREE The association of common single nucleotide polymorphisms (SNPs) was examined in PDK4 [-208A/G (rs10085637), IVS3+192C/T (rs3779478), IVS6+31A/G (rs2301630), IVS7+514A/G (rs12668651), IVS10+75C/T (rs10247649)] with type 2 diabetes and metabolic syndrome in 651 Korean subjects with type 2 diabetes and 350 nondiabetic Korean subjects. 22019269

2012

dbSNP: rs10258074
rs10258074
0.700 GeneticVariation GWASDB Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. 22158537

2012

dbSNP: rs10258162
rs10258162
0.700 GeneticVariation GWASDB Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. 22158537

2012