Gene: TCF7L2 ×
Source: GWASCAT ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT A genome-wide association study identifies novel risk loci for type 2 diabetes. 17293876

2007
dbSNP: rs7903146
rs7903146
TCF7L2
0.900 GeneticVariation GWASCAT A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. 17460697

2007
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. 17463246

2007
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. 17463248

2007
dbSNP: rs7901695
rs7901695
TCF7L2
C 0.900 GeneticVariation GWASCAT Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. 17463249

2007
dbSNP: rs4506565
rs4506565
TCF7L2
T 0.870 GeneticVariation GWASCAT Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. 17554300

2007
dbSNP: rs7903146
rs7903146
TCF7L2
A 0.900 GeneticVariation GWASCAT Type 2 diabetes whole-genome association study in four populations: the DiaGen consortium. 17668382

2007
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. 18372903

2008
dbSNP: rs7903146
rs7903146
TCF7L2
0.900 GeneticVariation GWASCAT Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data. 19056611

2009
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population. 19401414

2009
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia. 19734900

2009
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. 20581827

2010
dbSNP: rs7903146
rs7903146
TCF7L2
A 0.900 GeneticVariation GWASCAT A genome-wide association study of the metabolic syndrome in Indian Asian men. 20694148

2010
dbSNP: rs7901695
rs7901695
TCF7L2
0.900 GeneticVariation GWASCAT Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. 21347282

2011
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Subsequent GWAS using data from five institutions replicated the TCF7L2 gene variant (rs7903146) previously associated with T2D. 22101970

2012
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. 22693455

2012
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. 22885922

2012
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21. 23209189

2013
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India. 23300278

2013
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Genome-wide association study identifies three novel loci for type 2 diabetes. 23945395

2014
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico. 24390345

2014
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. 24509480

2014
dbSNP: rs7903146
rs7903146
TCF7L2
T 0.900 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes. 25102180

2014
dbSNP: rs34872471
rs34872471
TCF7L2
C 0.700 GeneticVariation GWASCAT T2DM GWAS in the Lebanese population confirms the role of TCF7L2 and CDKAL1 in disease susceptibility. 25483131

2014
dbSNP: rs34872471
rs34872471
TCF7L2
C 0.700 GeneticVariation GWASCAT Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes. 26818947

2016