Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE The minor allele (T) in rs9939609 was significantly higher (P=0.0001) in T2DM (31.25%) when compared with that of the control obese group (20%). 28603074

2017

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE Variants (such as rs9939609) in the fat mass- and obesity-associated (FTO) gene have been associated with obesity, type 2 diabetes, some cancers, and alcohol consumption. 23771786

2013

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE This was a cross-sectional study of 236 patients with type 2 diabetes (age 60.0 ± 10.3 years; diabetes duration 12.7 ± 8.2 years; 53.4% females) who were genotyped for FTO rs9939609. 23689376

2013

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE We investigated the association between genetic variants in FTO (rs9939609) and near MC4R (rs17782313) with obesity- and type 2 diabetes (T2DM)-related traits in a longitudinal birth cohort of 2,151 healthy individuals from the Vellore birth cohort in South India. 22421923

2012

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE We investigated potential interactions between body mass index (BMI) and genotypes of human leukocyte antigen (HLA), TCF7L2-rs7903146, and FTO-rs9939609 in relation to the risk of latent autoimmune diabetes in adults (LADA) and type 2 diabetes. 31125083

2019

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE The increased fat mass in carriers of the A allele of rs9939609 of FTO is associated not only with increased risk of type 2 diabetes, but also with an increase in atherogenic lipid profile and myocardial infarction in these patients. 20031593

2009

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE Recent genome-wide association studies have showed that common variant (rs9939609) in fat mass and obesity associated (FTO) gene was significantly associated with type 2 diabetes through an effect on human body mass index/obesity. 22311015

2012

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE Previous genome-wide association studies for type 2 diabetes susceptibility genes have confirmed that a common variant, rs9939609, in the fat mass and obesity associated (FTO) gene region is associated with body mass index (BMI) in European children and adults. 20598163

2010

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE Using MGA, some common gene variants were found to have little (<5%) but significant impact on the heritability of T2D related QTs [KCNJ11 (rs5219), p=0.004]; [IGF2BP2 (rs4402960), p=0.02]; [SLC30A8 (rs13266634), p=0.05]; [CAPN10 (rs2975760), p=0.031]; [FTO (rs8050136), p=0.023]; [FTO (rs9939609), p=0.018] and [SLC30A8 (rs13266634), p=0.05]. 24993573

2014

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE However, no significant association was found between genetics and risk of type 2 diabetes after control of potential confounders (at least for BMI) either for rs9939609 (fixed effect OR=1.05, 95% CI=0.97,1.13) or for rs8050136 polymorphism (fixed effect OR =1.07, 95%CI: 0.99, 1.16). 20337217

2009

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE A total of 236 patients with type 2 diabetes (age: 60.0 ± 10.3 years; diabetes duration: 12.7 ± 8.2 years; 53.4% women) were genotyped for the FTO rs7204609 and rs9939609 polymorphisms (ABI PRISM 7000 Real-Time PCR System). 21741858

2012

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE This study aimed to investigate the association of FTO rs9939609 and MC4R rs17782313 with anthropometric indexes, BP, and type 2 diabetes mellitus among hypertensive patients. 23849767

2013

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE The meta-analysis revealed a highly significant association for rs9939609 with both type 2 diabetes (OR 1.13; P = 4.5 × 10(-8)) and the risk to develop incident type 2 diabetes (OR 1.16; P = 3.2 × 10(-8)). 21398525

2011

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE None of the variants including previously reported intron 1 variants (rs1421085, rs8050136, rs9939609 and rs9930506) showed body mass index (BMI)-dependent/independent association with type 2 diabetes. 21814223

2011

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE The fat mass- and obesity-associated gene rs9939609 SNP is strongly associated with risk of obesity and newly diagnosed T2D in the Chinese population. 20186840

2010

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE The fat mass and obesity-associated gene (FTO) rs9939609 and peroxisome proliferator-activated receptor gamma 2 gene (PPARG2) rs1801282 polymorphisms are type 2 diabetes mellitus susceptibility gene variants associated with obesity. 24969838

2014

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE Recently an association was demonstrated between the single nucleotide polymorphism (SNP), rs9939609, within the FTO locus and obesity as a consequence of a genome wide association (GWA) study of type 2 diabetes in adults. 18335027

2008

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE The variant rs9939609 of the FTO gene was associated with T2DM in Palestine. 30170548

2018

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE Our data suggest that the associations between <i>FTO</i> rs9939609, rs8050136 and T2DM are region-related, and the two single-nucleotide polymorphisms contribute to an increased risk of T2DM. 28208657

2017

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE The meta-analysis of PPARγ2 (rs1801282) showed population-specific </span>association for T2D susceptibility as oppo</span>sed to FTO (rs9939609) which showed no difference in population effect toward T2D susceptibility. 26243686

2016

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE Recent studies identified the rs9939609 A-allele of the FTO (fat mass and obesity associated) gene as being associated with obesity and type 2 diabetes. 18984658

2009

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE We analysed rs9939609 in two studies of Pakistani individuals: 1666 adults aged ≥40 years from the Karachi population-based Control of Blood Pressure and Risk Attenuation (COBRA) study and 2745 individuals of Punjabi ancestry who were part of a Type 2 diabetes case-control study (UK Asian Diabetes Study/Diabetes Genetics in Pakistan; UKADS/DGP). 21294771

2011

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE The FTO-rs9939609 minor allele increased risk of obesity by 1.25-fold/allele (p = 9.0 × 10(-19)), overweight by 1.13-fold/allele (p = 1.0 × 10(-11)) and type 2 diabetes by 1.15-fold/allele (p = 5.5 × 10(-8)). 22109280

2012

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE Our findings indicate that the two variants (rs9939609 and rs8050136) in the FTO gene contribute to obesity and T2D in the Asian populations. 20057365

2010

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE In this case-control study, the associations of rs2241766 T/G of ADIPOQ, rs9289231 T/G of KALRN, and rs9939609 A/T of FTO polymorphisms with genetic susceptibility to CAD in type 2 diabetic (T2D) patients were investigated. 27218147

2016