rs8050136
|
|
|
0.900 |
GeneticVariation |
GWASDB |
In the "obese-type 2 diabetes" scan, FTO variants had the strongest type 2 diabetes effect (rs8050136: relative risk [RR] 1.49 [95% CI 1.34-1.66], P = 1.3 x 10(-13)), with only weak evidence for TCF7L2 (rs7901695 RR 1.21 [1.09-1.35], P = 0.001).
|
19056611 |
2009 |
rs8050136
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Single nucleotide polymorphisms in WFS1 rs10010131, CDKN2A/B rs10811661, CDC123/CAMK1D rs12779790, JAZF1 rs864745, FTO rs8050136, and HHEX/IDE rs5015480 were associated with T2DM and impaired glucose regulation.
|
23298195 |
2013 |
rs8050136
|
|
|
0.900 |
GeneticVariation |
BEFREE |
However, no significant association was found between genetics and risk of type 2 diabetes after control of potential confounders (at least for BMI) either for rs9939609 (fixed effect OR=1.05, 95% CI=0.97,1.13) or for rs8050136 polymorphism (fixed effect OR =1.07, 95%CI: 0.99, 1.16).
|
20337217 |
2009 |
rs8050136
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Of type 2 diabetes-associated genes, the CC/CT genotypes of rs7961581 (TSPAN8) and the obesity-linked AA/AC genotypes of rs8050136 (FTO) were associated with LADA in general, but mainly in low anti-GAD LADA patients (P = 0.004 and P = 0.004, respectively).
|
19833889 |
2010 |
rs8050136
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Our findings indicate that the two variants (rs9939609 and rs8050136) in the FTO gene contribute to obesity and T2D in the Asian populations.
|
20057365 |
2010 |
rs8050136
|
|
|
0.900 |
GeneticVariation |
BEFREE |
SNP rs8050136 in FTO was nominally associated with type 2 diabetes [OR = 1.22 (95% CI 1.03-1.46), p = 0.025].
|
17928989 |
2007 |
rs8050136
|
|
|
0.900 |
GeneticVariation |
BEFREE |
In the "obese-type 2 diabetes" scan, FTO variants had the strongest type 2 diabetes effect (rs8050136: relative risk [RR] 1.49 [95% CI 1.34-1.66], P = 1.3 x 10(-13)), with only weak evidence for TCF7L2 (rs7901695 RR 1.21 [1.09-1.35], P = 0.001).
|
19056611 |
2009 |