Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.900 | GeneticVariation | BEFREE | To test this hypothesis, we genotyped 1,466 German subjects, with increased risk for type 2 diabetes, for single-nucleotide polymorphism rs8050136 in the FTO gene and estimated glucose tolerance and insulin sensitivity from an oral glucose tolerance test (OGTT). | 18535549 | 2008 |
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A | 0.900 | GeneticVariation | GWASDB | Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. | 17463249 | 2007 |
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A | 0.900 | GeneticVariation | GWASCAT | A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. | 17463248 | 2007 |
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A | 0.900 | GeneticVariation | GWASDB | A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. | 17463248 | 2007 |
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A | 0.900 | GeneticVariation | GWASCAT | Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. | 17463249 | 2007 |
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0.900 | GeneticVariation | BEFREE | FTO rs8050136 being associated with type 2 diabetes through its effect on obesity); differential linkage disequilibrium across studies of the identified genetic markers with the respective culprit polymorphisms (e.g., possibly the case for CDKAL1 polymorphisms or for rs9300039 and markers in linkage disequilibrium, as shown by additional studies); and potential bias. | 17786212 | 2007 |
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0.900 | GeneticVariation | BEFREE | SNP rs8050136 in FTO was nominally associated with type 2 diabetes [OR = 1.22 (95% CI 1.03-1.46), p = 0.025]. | 17928989 | 2007 |