|
rs10830963
|
|
|
0.900 |
GeneticVariation |
BEFREE |
We analyzed nine single-nucleotide polymorphisms (SNPs), including rs340874 (PROX1), rs4607517 (GCK), rs2191349 (DGKB-TMEM195), rs7034200 (GLIS3), rs10885122 (ADRA2A), rs174550 (FADS1), rs11605924 (CRY2), rs10830963 (MTNR1B) and rs35767 (IGF1). rs340874 (PROX1) and rs174550 (FADS1) were significantly associated with T2D (P=0.0078, OR: 1.12; and P=0.0071, OR: 1.12, respectively).
|
22992776 |
2012 |
|
rs10830963
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The G-allele of the single nucleotide polymorphism (SNP) rs10830963 in MTNR1B (melatonin receptor 1B gene) is associated with type 2 diabetes mellitus and glucose levels in adults.
|
21366812 |
2011 |
|
rs10830963
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The associations of rs10830963 and rs1562444 with type 2 diabetes and related traits were not significant in the additive, dominant and recessive models.
|
21470412 |
2011 |
|
rs10830963
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Our findings do not support participation of the MTNR1B gene variant rs10830963 in the well documented association between sleep disturbances and type 2 diabetes.
|
21380592 |
2011 |
|
rs10830963
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Two SNPs in melatonin receptor 1B gene, rs10830963 and rs1387153 showed significant associations with fasting plasma glucose levels and the risk of Type 2 Diabetes Mellitus (T2DM) in previous studies.
|
21658282 |
2011 |
|
rs10830963
|
|
|
0.900 |
GeneticVariation |
BEFREE |
MTNR1B rs10830963 was genotyped in a population-based cohort including 3,210 unrelated Chinese Hans from Beijing and Shanghai, and tested for associations with risk of type 2 diabetes, diabetes-related traits and sleep status.
|
20398260 |
2010 |
|
rs10830963
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The two polymorphisms were associated with FPG levels in the healthy individuals (P = 0.003 and P = 0.002, respectively), and the G allele of rs10830963 was also associated with an increased risk of Type 2 diabetes in our patient sample (odds ratio, 1.12; 95% confidence interval, 1.02-1.23; P = 0.024).
|
20536959 |
2010 |
|
rs10830963
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The genetic variant rs10830963 was associated with an increased risk of type 2 diabetes in our Han Chinese cohort (OR 1.16, 95% CI 1.03-1.31, p = 0.015).
|
19241057 |
2009 |
|
rs10830963
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The G-allele of MTNR1B rs10830963 increases risk of type 2 diabetes through a state of i-IFG and not through i-IGT.
|
19324940 |
2009 |