rs3792267
|
|
|
0.770 |
GeneticVariation |
BEFREE |
This study observed that the SNPs rs3792267 in CAPN10, rs1501299 in APM1, and rs3760776 in FUT6 might serve as potential susceptible biomarkers for T2DM in Uyghurs.
|
27374856 |
2016 |
rs3792267
|
|
|
0.770 |
GeneticVariation |
BEFREE |
We replicated the significant association of rs1801278 and rs3792267 SNPs of the IRS1 and CAPN10 genes with T2DM in the population of Hyderabad.
|
24612564 |
2014 |
rs3792267
|
|
|
0.770 |
GeneticVariation |
BEFREE |
The aim was to investigate the association between the CAPN10 gene single nucleotide polymorphisms (SNPs) -44 (rs2975760), -43 (rs3792267), -19 (rs3842570), and -63 (rs5030952) and type 2 diabetes mellitus in an Asian Indian population in Southern India.
|
20667559 |
2011 |
rs3792267
|
|
|
0.770 |
GeneticVariation |
BEFREE |
A significant overrepresentation of a haplotype comprising (rs3792267), (19) and rs3749166 (chi(2) = 5.3, P = 0.021) was seen in T2DM subjects.
|
20119856 |
2010 |
rs3792267
|
|
|
0.770 |
GeneticVariation |
BEFREE |
We examined the association of CAPN10 UCSNP-43 (rs3792267), UCSNP-19 (rs3842570), and UCSNP-63 (rs5030952) SNPs with T2D in 917 Tunisian T2D patients and 748 non-diabetic controls.CAPN10 genotyping was done by PCR-RFLP.
|
20470430 |
2010 |
rs3792267
|
|
|
0.770 |
GeneticVariation |
BEFREE |
CAPN10 (rs3792267) was marginally associated with T2D with OR=1.5 (p=0.08) when considering the model GG vs. AG/AA with risk allele G. ENPP1 (rs1044498) was not associated with T2D.
|
19643578 |
2009 |
rs3792267
|
|
|
0.770 |
GeneticVariation |
BEFREE |
Two CAPN10 single nucleotide polymorphisms (SNPs), the SNP43 (rs3792267) and the SNP44 (rs2975760), have been associated with T2D in some, but not all studies conducted in a wide range of ethnicities.
|
16857402 |
2006 |
rs3792267
|
|
A |
0.770 |
SusceptibilityMutation |
CLINVAR |
|
|
|
rs2975760
|
|
|
0.730 |
GeneticVariation |
BEFREE |
Using MGA, some common gene variants were found to have little (<5%) but significant impact on the heritability of T2D related QTs [KCNJ11 (rs5219), p=0.004]; [IGF2BP2 (rs4402960), p=0.02]; [SLC30A8 (rs13266634), p=0.05]; [CAPN10 (rs2975760), p=0.031]; [FTO (rs8050136), p=0.023]; [FTO (rs9939609), p=0.018] and [SLC30A8 (rs13266634), p=0.05].
|
24993573 |
2014 |
rs5030952
|
|
|
0.730 |
GeneticVariation |
BEFREE |
TCF7L2 rs7903146, KCNJ11 rs5219, PPARγ rs1801282 and CAPN10 rs3842570, rs3792267, and rs5030952 were typed and associations with type 2 diabetes and phenotypic traits examined.
|
24059590 |
2013 |
rs2975760
|
|
|
0.730 |
GeneticVariation |
BEFREE |
The aim was to investigate the association between the CAPN10 gene single nucleotide polymorphisms (SNPs) -44 (rs2975760), -43 (rs3792267), -19 (rs3842570), and -63 (rs5030952) and type 2 diabetes mellitus in an Asian Indian population in Southern India.
|
20667559 |
2011 |
rs5030952
|
|
|
0.730 |
GeneticVariation |
BEFREE |
The aim was to investigate the association between the CAPN10 gene single nucleotide polymorphisms (SNPs) -44 (rs2975760), -43 (rs3792267), -19 (rs3842570), and -63 (rs5030952) and type 2 diabetes mellitus in an Asian Indian population in Southern India.
|
20667559 |
2011 |
rs5030952
|
|
|
0.730 |
GeneticVariation |
BEFREE |
We examined the association of CAPN10 UCSNP-43 (rs3792267), UCSNP-19 (rs3842570), and UCSNP-63 (rs5030952) SNPs with T2D in 917 Tunisian T2D patients and 748 non-diabetic controls.CAPN10 genotyping was done by PCR-RFLP.
|
20470430 |
2010 |
rs2975760
|
|
|
0.730 |
GeneticVariation |
BEFREE |
Two CAPN10 single nucleotide polymorphisms (SNPs), the SNP43 (rs3792267) and the SNP44 (rs2975760), have been associated with T2D in some, but not all studies conducted in a wide range of ethnicities.
|
16857402 |
2006 |
rs2975760
|
|
C |
0.730 |
SusceptibilityMutation |
CLINVAR |
|
|
|
rs5030952
|
|
T |
0.730 |
SusceptibilityMutation |
CLINVAR |
|
|
|
rs3842570
|
|
|
0.720 |
GeneticVariation |
BEFREE |
The aim was to investigate the association between the CAPN10 gene single nucleotide polymorphisms (SNPs) -44 (rs2975760), -43 (rs3792267), -19 (rs3842570), and -63 (rs5030952) and type 2 diabetes mellitus in an Asian Indian population in Southern India.
|
20667559 |
2011 |
rs3842570
|
|
|
0.720 |
GeneticVariation |
BEFREE |
We examined the association of CAPN10 UCSNP-43 (rs3792267), UCSNP-19 (rs3842570), and UCSNP-63 (rs5030952) SNPs with T2D in 917 Tunisian T2D patients and 748 non-diabetic controls.CAPN10 genotyping was done by PCR-RFLP.
|
20470430 |
2010 |
rs3842570
|
|
AGATGATTCTGTCCCAGGAGCCGGGAGGAGGGT |
0.720 |
SusceptibilityMutation |
CLINVAR |
|
|
|
rs41266971
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Sib-TDT analysis showed that some gene variants were significantly associated with T2D risk but didn't reach the level of significance after Bonferroni correction [KCNJ11 (rs5219), p=0.047] and [CAPN10 (rs41266971), p=0.035].
|
24993573 |
2014 |
rs769690789
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In fact, we evaluated the effect of seven polymorphisms in the following genes-PPARg (Pro12Ala), TNFα (-308A/G), ENPP1(K121Q), TCF7L2(rs7903146°C/T), MTHFR(C677T), ACE(I/D), and CAPN10(3R/2R)-on T2D risk, through a meta-analysis combining data of previous studies performed on Tunisian populations originating from the north, center, or south of the country.
|
23249316 |
2012 |
rs3749166
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A significant overrepresentation of a haplotype comprising (rs3792267), (19) and rs3749166 (chi(2) = 5.3, P = 0.021) was seen in T2DM subjects.
|
20119856 |
2010 |
rs7607759
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Another polymorphism, UCSNP-44, which is in linkage disequilibrium with a coding single-nucleotide polymorphism (Thr504Ala), has subsequently been associated with type 2 diabetes in extensive meta-analyses.
|
15930958 |
2005 |