rs1044498
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Different statistical models revealed that all the dominant models were found associated in between alleles for disease risk (p < 0.001) while no association of PC-1 rs1044498 (K121Q) polymorphism was found with insulin-resistant parameters in T2DM cases.
|
31250990 |
2019 |
rs1044498
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In this study, association of K121Q (rs1044498) polymorphism of the ENPP1 gene with T2DM and bone disorders is evaluated.
|
28942038 |
2017 |
rs1044498
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our study indicates that the ENPP1 rs1044498 SNP is associated with T2D, waist circumference, and fasting glucose in Taiwanese subjects.
|
27238374 |
2016 |
rs1044498
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Under an additive genetic model, the C allele of ADRB3-rs4994, the C allele of ENPP1-rs1044498, and the A allele of PPARGC1A-rs8192678 increase the risk of type 2 diabetes in the Chinese Han population.
|
22391941 |
2012 |
rs1044498
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Allelic and genotypic analyses showed significant main effects of ENPP1 rs1044498 (P = 0.000005 and 0.00007, respectively) on the risk of T2D after Bonferroni correction (P < 0.05/2 = 0.025).
|
23111648 |
2012 |
rs1044498
|
|
|
0.100 |
GeneticVariation |
BEFREE |
For this reason, the present study looked at the contribution of ENNP1 (rs1044498), IGF2BP2 (rs1470579), KCNJ11 (rs5219), MLXIPL (rs7800944), PPARγ (rs1801282), SLC30A8 (rs13266634) and TCF7L2 (rs7903146) SNPs to the risk of T2DM in Lebanese and Tunisian Arabs.
|
22749234 |
2012 |
rs1044498
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The K121Q (rs1044498) single nucleotide polymorphism (SNP) in the ENPP1 gene has shown association with insulin resistance and type 2 diabetes in various ethnic populations.
|
20091022 |
2010 |
rs1044498
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The K121Q (lysine to glutamine substitution at amino acid 121, encoded by single-nucleotide polymorphism rs1044498) variant of the ectonucleotide pyrophosphatase/phosphodiesterase gene (ENPP1) has been associated with insulin resistance and related vascular complications in patients with type 2 diabetes (T2D) in many, although not all, studies.
|
18950909 |
2009 |
rs1044498
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Ectoenzyme nucleotide pyrophosphatase phosphodiesterase 1 (ENPP1) inhibits insulin signaling, and a recent meta-analysis reported a nominal association between the Q allele in the K121Q (rs1044498) single nucleotide polymorphism in its gene ENPP1 and type 2 diabetes.
|
19017751 |
2009 |
rs1044498
|
|
|
0.100 |
GeneticVariation |
BEFREE |
CAPN10 (rs3792267) was marginally associated with T2D with OR=1.5 (p=0.08) when considering the model GG vs. AG/AA with risk allele G. ENPP1 (rs1044498) was not associated with T2D.
|
19643578 |
2009 |