Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.070 | GeneticVariation | BEFREE | We suggest that the PPARA L162V polymorphism may have diverse effects on serum lipids and CHD risk depends on the presence of T2DM. | 23583468 | 2013 |
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0.070 | GeneticVariation | BEFREE | According to our study, the L162V SNP does not have a strong impact on the pathogenesis of type 2 diabetes or obesity. | 18726867 | 2009 |
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0.070 | GeneticVariation | BEFREE | In conclusion, in a relative large-scale study of middle-aged whites we found no evidence of association between the PPARalpha Leu162Val polymorphism and obesity or type 2 diabetes. | 17129741 | 2007 |
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0.070 | GeneticVariation | BEFREE | We examined association between three PPARalpha gene polymorphisms (an A-->C variant in intron 1, the L162V variant, and the intron 7 G-->C variant) and age at diagnosis of type 2 diabetes in 912 Caucasian type 2 diabetic subjects. | 15677519 | 2005 |
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0.070 | GeneticVariation | BEFREE | Association between the PPARalpha L162V polymorphism, plasma lipoprotein levels, and atherosclerotic disease in patients with diabetes mellitus type 2 and in nondiabetic controls. | 15199365 | 2004 |
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0.070 | GeneticVariation | BEFREE | A polymorphism, L162V, in the peroxisome proliferator-activated receptor alpha (PPARalpha) gene is associated with lower body mass index in patients with non-insulin-dependent diabetes mellitus. | 11409711 | 2001 |
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0.070 | GeneticVariation | BEFREE | We subsequently screened a sample of 121 patients newly diagnosed with type 2 diabetes and their age and sex-matched nondiabetic controls, recruited from the Saguenay-Lac-St-Jean region of Northeastern Quebec, for the presence of the L162V mutation by a PCR-RFLP based method. | 10828087 | 2000 |