Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1800562
rs1800562
0.100 GeneticVariation BEFREE But our results showed a relationship between C282Y mutation and NAFLD in persons with type 2 diabetes. 27894410

2016

dbSNP: rs1800562
rs1800562
0.100 GeneticVariation BEFREE Diabetes in first-degree family members: a predictor of type 2 diabetes in 159 nonscreening Alabama hemochromatosis probands with HFE C282Y homozygosity. 23990522

2014

dbSNP: rs1800562
rs1800562
0.100 GeneticVariation BEFREE There was an association of type 2 DM with H63D polymorphism (genotypes HD/DD: OR=1.7, 95% CI=1.2-2.6), but not with C282Y polymorphism (OR=0.7, 955 CI=0.4-1.4). 20097100

2011

dbSNP: rs1800562
rs1800562
0.100 GeneticVariation BEFREE C282Y and H63D are the main mutations related to hereditary hemochromatosis; these mutations have been reported to be associated with increased risk of developing diabetes mellitus type 2 (DM2). 19876870

2009

dbSNP: rs1800562
rs1800562
0.100 GeneticVariation BEFREE Our data indicate significant effects of H63D and C282Y on body iron stores and suggest a potential interaction between HFE genotypes and heme iron intake in relation to the risk of type 2 diabetes. 16306377

2005

dbSNP: rs1800562
rs1800562
0.100 GeneticVariation BEFREE In conclusion, we failed to demonstrate that the C282Y and H63D HFE gene mutations were risk factors for CAD in Caucasians with type 2 diabetes lasting longer than 10 years. 15222129

2004

dbSNP: rs1800562
rs1800562
0.100 GeneticVariation BEFREE We initiated the present work to determine whether the presence of the HFE C282Y or H63D mutations could be related to the clinical expression of diabetes mellitus type 2. 15347835

2004

dbSNP: rs1800562
rs1800562
0.100 GeneticVariation BEFREE We found no evidence for the association of the C282Y mutation with T2DM. 12601293

2003

dbSNP: rs1800562
rs1800562
0.100 GeneticVariation BEFREE These data suggest that heterozygosity for C282Y might be a novel risk factor for PDR in Caucasians with type 2 diabetes. 14618419

2003

dbSNP: rs1800562
rs1800562
0.100 GeneticVariation BEFREE Relations among serum ferritin, C282Y and H63D mutations in the HFE gene and type 2 diabetes mellitus in the Czech population. 12148086

2002

dbSNP: rs1800562
rs1800562
0.100 GeneticVariation BEFREE We performed an association study to assess the role of the C282Y and H63D mutations in the HFE gene as a risk factor for type 2 diabetes and diabetic nephropathy. 11423500

2001