Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1800795
rs1800795
0.070 GeneticVariation BEFREE An association of the rs1800795 SNP of the IL-6 gene with T2D has been detected for the first time in Cretans. 29957071

2018

dbSNP: rs1800795
rs1800795
0.070 GeneticVariation BEFREE IL-6 genotypes of rs1800795 GC and rs1800796 GG might point to a relatively high risk for T2D patients suffering from PDR in a Chinese population and they were associated with elevation of IL-6 expression in both mRNA and protein. 28651253

2017

dbSNP: rs1800795
rs1800795
0.070 GeneticVariation BEFREE Interleukin-6 (IL-6)-597 A/G (rs1800797) & -174 G/C (rs1800795) gene polymorphisms in type 2 diabetes. 25222779

2014

dbSNP: rs1800795
rs1800795
0.070 GeneticVariation BEFREE Recent studies identified a significant interaction between body mass index (BMI) and the rs1800795 polymorphism of the interleukin-6 gene that influences both IR and onset of type 2 diabetes mellitus, with obese individuals homozygous for the C allele demonstrating the highest level of IR and greatest risk for type 2 diabetes mellitus. 22075267

2012

dbSNP: rs1800795
rs1800795
0.070 GeneticVariation BEFREE This study examined a possible association of the G>C polymorphism at nucleotide -174 in the promoter region of the interleukin-6 (IL-6) gene (rs1800795) with the prevalence of diabetic complications in 235 patients with type 1 and 498 patients with type 2 diabetes. 19140096

2009

dbSNP: rs1800795
rs1800795
0.070 GeneticVariation BEFREE Several studies have investigated associations between the -174G>C single nucleotide polymorphism (rs1800795) of the IL6 gene and phenotypes related to type 2 diabetes mellitus (T2DM) but presented inconsistent results. 18752089

2009

dbSNP: rs1800795
rs1800795
0.070 GeneticVariation BEFREE Two common polymorphisms in the promoter of the IL-6 encoding gene IL6, -174G>C (rs1800795) and -573G>C (rs1800796), have been investigated for association with type 2 diabetes in numerous studies but with results that have been largely equivocal. 17003362

2006