Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2237897
rs2237897
C 0.880 GeneticVariation GWASCAT Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population. 30718926

2019

dbSNP: rs2237897
rs2237897
0.880 GeneticVariation BEFREE In the first stage, SNPs rs1552224 at CENTD2 were significantly associated with T2D and the association was statistically significant in the whole study population (P = 0.001) although it was not replicated in the second stage. rs1552224 and rs2237897 of KCNQ1 showed significant joint effect on T2D and there was a significant decreased risk of T2D with the number increase of risk alleles (P for trend = 3.81 × 10(-17)). 25749274

2015

dbSNP: rs2237897
rs2237897
C 0.880 GeneticVariation GWASCAT Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico. 24390345

2014

dbSNP: rs2237897
rs2237897
C 0.880 GeneticVariation GWASDB Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico. 24390345

2014

dbSNP: rs2237897
rs2237897
0.880 GeneticVariation BEFREE We aimed to evaluate the effect of four common variants (rs2237892, rs2283228, rs2237895, and rs2237897) in KCNQ1 on susceptibility of type 2 diabetes (T2D) by performing a case-control study as well as a comprehensive meta-analysis. 23786590

2013

dbSNP: rs2237897
rs2237897
0.880 GeneticVariation BEFREE Seven of the 29 single nucleotide polymorphisms (SNPs) examined were found to be associated with T2D risk at P ≤ 0.05, including rs6769511 (IGF2BP2), 2 SNPs in the WFS1 gene (rs4689388 and rs1801214), rs7903146 (TCF7L2), and 3 SNPs in the KCNQ1 gene (rs231362, rs2237892, and rs2237897). 23144361

2012

dbSNP: rs2237897
rs2237897
0.880 GeneticVariation GWASDB A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese. 20174558

2010

dbSNP: rs2237897
rs2237897
0.880 GeneticVariation BEFREE Four single nucleotide polymorphisms (SNPs, rs2237892, rs2237895, rs2237897, rs2283228) in KCNQ1 are associated with type 2 diabetes mellitus in different ancestral groups. 19575309

2010

dbSNP: rs2237897
rs2237897
0.880 GeneticVariation BEFREE Combined analysis by a meta-analysis revealed that the T allele of rs2237897 was significantly associated with susceptibility to diabetic nephropathy in Japanese subjects with type 2 diabetes (odds ratio 1.22 [95% CI 1.10-1.34], P = 3.1 x 10(-4), corrected P = 0.01). 20056949

2010

dbSNP: rs2237897
rs2237897
0.880 GeneticVariation BEFREE Four single nucleotide polymorphisms (SNPs) (rs2237892, rs2237895, rs2237897, and rs2283228) in KCNQ1 are reported to be associated with type 2 diabetes mellitus (T2DM), possibly caused by a reduction in insulin secretion and higher fasting glucose, but the results are inconsistent. 20701788

2010

dbSNP: rs2237897
rs2237897
0.880 GeneticVariation BEFREE Notably, the associations with type 2 diabetes were markedly attenuated after adjusting for HOMA-B (OR(rs2237892): 1.33 [1.05-1.68], P = 0.018; OR(rs2237895): 1.24 [1.00-1.54], P = 0.0524; OR(rs2237897): 1.22[0.98-1.53], P = 0.09). 19556355

2009

dbSNP: rs2237897
rs2237897
C 0.880 GeneticVariation GWASCAT The association of these SNPs with type 2 diabetes was replicated in samples from Singaporean (additive model: rs2237895, P = 8.5 x 10(-3); OR = 1.14, rs2237897, P = 2.4 x 10(-4); OR = 1.22) and Danish populations (additive model: rs2237895, P = 3.7 x 10(-11); OR = 1.24, rs2237897, P = 1.2 x 10(-4); OR = 1.36). 18711366

2008

dbSNP: rs2237897
rs2237897
C 0.880 GeneticVariation GWASDB The association of these SNPs with type 2 diabetes was replicated in samples from Singaporean (additive model: rs2237895, P = 8.5 x 10(-3); OR = 1.14, rs2237897, P = 2.4 x 10(-4); OR = 1.22) and Danish populations (additive model: rs2237895, P = 3.7 x 10(-11); OR = 1.24, rs2237897, P = 1.2 x 10(-4); OR = 1.36). 18711366

2008

dbSNP: rs2237897
rs2237897
0.880 GeneticVariation BEFREE Several other SNPs in the same linkage disequilibrium (LD) block were strongly associated with type 2 diabetes (additive model: rs2237895, P = 7.3 x 10(-9); OR = 1.32, 95% CI = 1.20-1.45, rs2237897, P = 6.8 x 10(-13); OR = 1.41, 95% CI = 1.29-1.55). 18711366

2008