Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2283228
rs2283228
A 0.760 GeneticVariation GWASCAT Genetics of Type 2 Diabetes in U.S. Hispanic/Latino Individuals: Results From the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). 28254843

2017

dbSNP: rs2283228
rs2283228
A 0.760 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes. 25102180

2014

dbSNP: rs2283228
rs2283228
0.760 GeneticVariation BEFREE In conclusion, this meta-analysis suggests that rs2237892, rs2237895, rs2237897, rs2283228, and rs231362 polymorphisms in KCNQ1 are associated with elevated T2D risk. 23271129

2013

dbSNP: rs2283228
rs2283228
0.760 GeneticVariation BEFREE We aimed to evaluate the effect of four common variants (rs2237892, rs2283228, rs2237895, and rs2237897) in KCNQ1 on susceptibility of type 2 diabetes (T2D) by performing a case-control study as well as a comprehensive meta-analysis. 23786590

2013

dbSNP: rs2283228
rs2283228
0.760 GeneticVariation BEFREE The haplotype TCA containing the allele of rs2237892 (T), rs2283228 (C) and rs2237895 (A) was highly protective against T2D (Second model; OR = 0.17, P = 3.7 × 10(-11)). 22016621

2011

dbSNP: rs2283228
rs2283228
0.760 GeneticVariation BEFREE Four single nucleotide polymorphisms (SNPs, rs2237892, rs2237895, rs2237897, rs2283228) in KCNQ1 are associated with type 2 diabetes mellitus in different ancestral groups. 19575309

2010

dbSNP: rs2283228
rs2283228
0.760 GeneticVariation BEFREE Four single nucleotide polymorphisms (SNPs) (rs2237892, rs2237895, rs2237897, and rs2283228) in KCNQ1 are reported to be associated with type 2 diabetes mellitus (T2DM), possibly caused by a reduction in insulin secretion and higher fasting glucose, but the results are inconsistent. 20701788

2010

dbSNP: rs2283228
rs2283228
0.760 GeneticVariation BEFREE SNPs rs2237897, rs2237892, and rs2283228 were significantly associated with type 2 diabetes (odds ratio [OR] 1.48, P = 3 x 10(-4); OR 1.38, P = 0.002; OR 1.31, P = 0.012, respectively). 19252135

2009