Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.830 | GeneticVariation | GWASCAT | Leveraging Polygenic Functional Enrichment to Improve GWAS Power. | 30595370 | 2019 |
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C | 0.830 | GeneticVariation | GWASCAT | Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes. | 29358691 | 2018 |
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T | 0.830 | GeneticVariation | GWASCAT | Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes. | 30054458 | 2018 |
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C | 0.830 | GeneticVariation | GWASCAT | Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease. | 28869590 | 2017 |
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0.830 | GeneticVariation | BEFREE | Genome-wide association studies have shown that the rs340874 single nucleotide polymorphism (SNP) in PROX1 is a genetic susceptibility factor for type 2 diabetes. | 23274905 | 2013 |
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0.830 | GeneticVariation | BEFREE | We analyzed nine single-nucleotide polymorphisms (SNPs), including rs340874 (PROX1), rs4607517 (GCK), rs2191349 (DGKB-TMEM195), rs7034200 (GLIS3), rs10885122 (ADRA2A), rs174550 (FADS1), rs11605924 (CRY2), rs10830963 (MTNR1B) and rs35767 (IGF1). rs340874 (PROX1) and rs174550 (FADS1) were significantly associated with T2D (P=0.0078, OR: 1.12; and P=0.0071, OR: 1.12, respectively). | 22992776 | 2012 |
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0.830 | GeneticVariation | GWASDB | Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. | 22885922 | 2012 |
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0.830 | GeneticVariation | BEFREE | Further adjusting age, gender and BMI as confounders found PROX1 rs340874 was associated with type 2 diabetes (p = 0.0391). | 21103350 | 2010 |