Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4430796
rs4430796
0.870 GeneticVariation BEFREE The results of this study indicate that the use of 8 genetic polymorphisms associated with carbohydrate and lipid metabolism and type 2 diabetes [<i>PTGS2</i> (<i>COX2</i>) rs6681231, <i>FADS1</i> rs174550, <i>HNF1B</i> rs4430796, <i>ADIPOQ</i> rs266729, <i>IL18</i> rs187238, <i>CCL2</i> rs1024611, <i>HHEX</i> rs5015480 and <i>CDKN2A/2B</i> rs10811661] together with clinical risk factors (BMI and age) may significantly improve the prediction of GDM. 31299695

2019

dbSNP: rs4430796
rs4430796
A 0.870 GeneticVariation GWASCAT Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease. 28869590

2017

dbSNP: rs4430796
rs4430796
G 0.870 GeneticVariation GWASCAT Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. 24509480

2014

dbSNP: rs4430796
rs4430796
G 0.870 GeneticVariation GWASDB Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. 24509480

2014

dbSNP: rs4430796
rs4430796
0.870 GeneticVariation BEFREE Nominal interactions were observed for sleep duration and PPARG rs1801282, CRY2 rs7943320 and HNF1B rs4430796 in influencing risk of type 2 diabetes (p < 0.05). 24280871

2014

dbSNP: rs4430796
rs4430796
G 0.870 GeneticVariation GWASDB A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans. 22961080

2013

dbSNP: rs4430796
rs4430796
G 0.870 GeneticVariation GWASCAT A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans. 22961080

2013

dbSNP: rs4430796
rs4430796
0.870 GeneticVariation BEFREE COL8A1 rs792837 (P=2.9 × 10(-9)), KCNQ1 rs2237892 (P=1.8 × 10(-18)) and rs2237895 (P=0.002), ALX4 rs729287 (Pc=7.5 × 10(-5)), and HNF1 rs4430796 (P=0.003) were significantly associated with T2DM, with similar effect sizes to those of Europeans. 24145053

2013

dbSNP: rs4430796
rs4430796
0.870 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. 22325160

2012

dbSNP: rs4430796
rs4430796
0.870 GeneticVariation BEFREE Besides, the haplotype-based analysis demonstrated that AGT in block rs752010-rs4430796-rs7501939 was associated with about 30% increase in T2D risk (OR 1.31, 95% CI 1.09-1.57, P = 0.01). 23300827

2012

dbSNP: rs4430796
rs4430796
0.870 GeneticVariation BEFREE We identified an endometrial cancer susceptibility locus close to HNF1B at 17q12 (rs4430796, P = 7.1 × 10(-10)) that is also associated with risk of prostate cancer and is inversely associated with risk of type 2 diabetes. 21499250

2011

dbSNP: rs4430796
rs4430796
0.870 GeneticVariation BEFREE Consistent with the initial study, we observed evidence that the risk G allele of rs4430796 in intron 2 was significantly associated with type 2 diabetes (odds ratio 1.16 [95% CI 1.05-1.29], P = 0.0035, empirical P = 0.0475). 19168595

2009

dbSNP: rs4430796
rs4430796
0.870 GeneticVariation BEFREE Where type 2 diabetes was the outcome, only one statistically significant interaction effect was observed, and this was for the HNF1B rs4430796 variant (P(interaction) = 0.0004). 19324937

2009