Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE Angiotensinogen (AGT) gene missense polymorphisms (rs699 and rs4762) and diabetic nephropathy in Caucasians with type 2 diabetes mellitus. 28488548

2017

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE The aim of the current study was to investigate the association between the InDel polymorphism in the angiotensin I-converting enzyme gene (ACE) and the rs699 polymorphism in the angiotensinogen gene (AGT) and diabetes mellitus type 2 (DM2) in a sample population from Southern Brazil. 26782563

2015

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE The aim of this study was to evaluate the relationship of AGT M235T and apoprotein E (APO E) gene polymorphism with DN in Turkish patients of Type 2 diabetes, and to compare genotype and allele distributions among DN patients, non-DN patients, and healthy controls. 21500980

2011

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE The association between renin C-4063T and angiotensinogen (AGT) T174M, M235T, and A-6G polymorphisms with diabetic nephropathy (DN) was investigated in Tunisian type 2 diabetes (T2DM) patients. 21421655

2011

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE To explore the role of genetic variants of angiotensinogen (AGT M235T), angiotensin-converting enzyme (ACE I/D), and angiotensin type 1 receptor (AT1R A1166C) as predictors of diabetes risk and to examine their combined effects on type 2 diabetes mellitus (T2DM) patients. 20580725

2010

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE Gender-dependent effect of ACE I/D and AGT M235T polymorphisms on the progression of urinary albumin excretion in Taiwanese with type 2 diabetes. 18849600

2009

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE There were no differences in the frequencies of the AGT M235T and ACE I/D genotypes between Turkish patients with type 2 DM with and without nephropathy. 18413162

2008

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE ACE I/D polymorphism, but not AGT M235T polymorphism, may affect polyneuropathy development in type 2 diabetes without macroalbuminuria. 12449516

2003

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE Our study provided evidence against an association between angiotensinogen M235T or chymase gene CMA/B polymorphisms and the presence of incipient or overt nephropathy in Caucasian patients with type II diabetes. 11096141

2000

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE Our study revealed RAS genes, ACE and AGT-M235T but not AGT-T174M, AGTR1 or REN genotypes, as contributing factors for DN in type 2 diabetes mellitus in Chinese. 11776100

2000

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE AGT gene M235T polymorphism is associated with diabetic nephropathy in NIDDM. 11717948

1999

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE We compared the frequencies of the AGT promoter and M235T polymorphisms among three subgroups of adult Oji-Cree: 50 subjects who had type 2 diabetes with microalbuminuria, 6 subjects who had type 2 diabetes without albuminuria and 302 non-diabetic, normotensive subjects. 10383081

1999

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE The data do not support a role of ACE (DD/II) or Atg M235T polymorphism in the development of diabetic nephropathy in Chinese patients with type II diabetes, and no synergistic effect was found between them. 10352194

1999

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE DNA polymorphism M235T in the angiotensinogen gene, which is associated with higher expression of this gene, contributes to the risk of diabetic nephropathy in NIDDM men but not in women. 9535411

1998

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE We studied the relationship of either an insertion-deletion polymorphism in the angiotensin-converting enzyme (ACE) gene and the M235T and T174M variant polymorphisms of the angiotensinogen (AGT) gene in non-insulin-dependent diabetes mellitus (NIDDM) patients and its relationship with cardiovascular complications. 9258285

1997