Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE We investigated potential interactions between body mass index (BMI) and genotypes of human leukocyte antigen (HLA), TCF7L2-rs7903146, and FTO-rs9939609 in relation to the risk of latent autoimmune diabetes in adults (LADA) and type 2 diabetes. 31125083

2019

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE Omentin V109D and FTO rs9939609 genetic variations may change insulin metabolism and have key roles in developing T2D through insulin resistance. 31200723

2019

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE For the rs9939609 variant (FTO), the dominant model AA/(AT+TT) revealed significant association with T2D [odds ratio (OR)=2.03, P=0.021], but was non-significant post correction for multiple testing (P=0.002). 31823921

2019

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE So, the aim of this study was to investigate the relationship between FTO variants (rs763967273, rs759031579, rs141115189, rs9926289, rs76804286 and rs9939609) with T2DM, serum apelin and androgenic hormones in Iranian obese women. 29101069

2018

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE The variant rs9939609 of the FTO gene was associated with T2DM in Palestine. 30170548

2018

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE Our data suggest that the associations between <i>FTO</i> rs9939609, rs8050136 and T2DM are region-related, and the two single-nucleotide polymorphisms contribute to an increased risk of T2DM. 28208657

2017

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE ADORA/rs903361, CADM2/rs13078807, GNPDA2/rs10938397, VEGFA/rs6905288 and FTO/rs9939609 are associated with an increased risk of pediatric-onset type 2 diabetes in the Mexican population. 28401323

2017

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE The minor allele (T) in rs9939609 was significantly higher (P=0.0001) in T2DM (31.25%) when compared with that of the control obese group (20%). 28603074

2017

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE After excluding four SNPs due to Hardy-Weinberg disequilibrium, significant associations in age-matched cohorts were found betweenT2DM and the following SNPs: rs9939609 (FTO), rs13266634 (SLC30A8), rs7961581 (TSPAN8/LGR5), and rs1799883 (FABP2). 28738793

2017

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE The meta-analysis of PPARγ2 (rs1801282) showed population-specific association for T2D susceptibility as opposed to FTO (rs9939609) which showed no difference in population effect toward T2D susceptibility. 26243686

2016

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE CONCLUSIONS Polymorphisms in CDKN2A/2B and FTO, but not CDKAL1, may be associated with T2D, and alleles rs8050136 and rs9939609 are likely risk alleles for T2D in this population. 26873362

2016

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE Three T2D associated risk variants were individually associated with breast cancer risk after adjustment for multiple comparisons using the Bonferroni method (at p < 0.001), rs9939609 (FTO) (OR 0.94, 95 % CI = 0.92-0.95, p = 4.13E-13), rs7903146 (TCF7L2) (OR 1.04, 95 % CI = 1.02-1.06, p = 1.26E-05), and rs8042680 (PRC1) (OR 0.97, 95 % CI = 0.95-0.99, p = 8.05E-04). 27053251

2016

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE In this case-control study, the associations of rs2241766 T/G of ADIPOQ, rs9289231 T/G of KALRN, and rs9939609 A/T of FTO polymorphisms with genetic susceptibility to CAD in type 2 diabetic (T2D) patients were investigated. 27218147

2016

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE The single nucleotide polymorphism rs9939609 of the gene FTO, which encodes fat mass and obesity-associated protein, is strongly associated with obesity and type 2 diabetes (T2D) in multiple populations; however, the underlying mechanism of this association is unclear. 27249024

2016

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE In the meta-analysis of 42 studies for 11 obesity/BMI-associated loci, we observed a statistically significant association of the FTO rs9939609 polymorphism (66 425 T2D cases/239 689 normoglycaemic subjects; P = 1·00 × 10(-41) ) and six other variants with T2D risk (17 915 T2D cases/27 531 normoglycaemic individuals: n = 40 629-130 001; all P < 0·001 for SH2B1 rs7498665, FAIM2 rs7138803, TMEM18 rs7561317, GNPDA2 rs10938397, BDNF rs925946 and NEGR1 rs2568958). 24528214

2014

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE The fat mass and obesity-associated gene (FTO) rs9939609 and peroxisome proliferator-activated receptor gamma 2 gene (PPARG2) rs1801282 polymorphisms are type 2 diabetes mellitus susceptibility gene variants associated with obesity. 24969838

2014

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE Using MGA, some common gene variants were found to have little (<5%) but significant impact on the heritability of T2D related QTs [KCNJ11 (rs5219), p=0.004]; [IGF2BP2 (rs4402960), p=0.02]; [SLC30A8 (rs13266634), p=0.05]; [CAPN10 (rs2975760), p=0.031]; [FTO (rs8050136), p=0.023]; [FTO (rs9939609), p=0.018] and [SLC30A8 (rs13266634), p=0.05]. 24993573

2014

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE The Fat Mass and Obesity-Associated Protein (FTO) gene rs9939609 single nucleotide polymorphism (SNP) has been associated with obesity, metabolic syndrome, insulin resistance (IR), and type 2 diabetes mellitus in the general population. 25367448

2014

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation GWASDB Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India. 23300278

2013

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE The FTO-rs9939609 polymorphism, systolic blood pressure, and waist-hip ratio were the most significant independent predictors for T2D, in which the power of the adjusted prediction model was 0.769. 23142383

2013

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE This was a cross-sectional study of 236 patients with type 2 diabetes (age 60.0 ± 10.3 years; diabetes duration 12.7 ± 8.2 years; 53.4% females) who were genotyped for FTO rs9939609. 23689376

2013

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE Variants (such as rs9939609) in the fat mass- and obesity-associated (FTO) gene have been associated with obesity, type 2 diabetes, some cancers, and alcohol consumption. 23771786

2013

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE This study aimed to investigate the association of FTO rs9939609 and MC4R rs17782313 with anthropometric indexes, BP, and type 2 diabetes mellitus among hypertensive patients. 23849767

2013

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE We confirmed association of SNPs in the first intron (rs11642015, rs62048402 and rs9939609) of FTO and rs7561317 representing the TMEM18 locus with T2D. 23860325

2013

dbSNP: rs9939609
rs9939609
FTO
0.900 GeneticVariation BEFREE Association of rs9939609 variant with higher FBG, plasma insulin, and leptin levels indicates that this polymorphism may disturb the metabolism in adult females and predispose them to obesity and type 2 diabetes. 24102053

2013